Sentences with phrase «therapeutic drugs»

They could be used for therapeutic drug screening and to help teach researchers how to grow whole human organs.
The scientific literature contains vast information about the adverse effects of therapeutic drugs.
They also use antibiotics and other therapeutic drugs when available.
So, most people don't know what to do when I tell them that my parents were the directors of a residential therapeutic drug community center.
We are talking therapeutic drugs, depression and divorce on this episode of the podcast.
Preformed drugs of abuse analysis and tested in the area of therapeutic drug monitoring prior to lab reorganization in Jan. 2011.
The first award will be used to investigate the unexplored parts of the so - called «druggable genome» — genes that have the potential to be used as future therapeutic drug targets.
The study also reveals new pockets in the protein that could be targeted with therapeutic drugs aimed at alleviating MODY1.
Furthermore, these results may lead to the development of new therapeutic drugs for kidney stone formation to control macrophage function.
«There are no new therapeutic drugs in development,» says Manjula Lusti - Narasimhan of the WHO's Department of Reproductive Health and Research.
Interactive sessions will present basic and clinic research focusing on advances in virology, therapeutic drug development and practical -LRB-...)
The finding, reported in tomorrow's issue of the Proceedings of the National Academy of Sciences, may help researchers narrow their search for a possible therapeutic drug against a condition that strikes one in 2000 male births.
It took the CTD team one year to efficiently extract information from those 88,000 papers about therapeutic drugs and their involvement in toxic endpoints, such as hypertension, seizures, kidney failure and liver disease.
We often send labwork to outside laboratories when testing for specific conditions or for monitoring therapeutic drug levels.
For now, Rashid's group has a list of candidate therapeutic drugs that they'll test in their new liver disease models, something that may still prove useful to patients.
«It's important to reintegrate alcohol and therapeutic drug reactions into the definition of poisoning in order to get a more accurate picture of the magnitude and burden of poisoning,» Friedman said.
«And while the tumor model we're now studying doesn't present targets for new drugs, if we can discover the mechanism controlling that model, it may yield therapeutic drug targets.»
The research team further tested these organoids — three - dimensional organ structures grown in the lab — and found that they could be used to model kidney development and susceptibility of the kidney tissue to therapeutic drug toxicity.
But non-antibiotic therapeutic drugs already approved for other purposes in people could be effective in fighting the antibiotic - resistant pathogens, according to a new study from researchers at The University of Texas Medical Branch at Galveston.
These results are important because they increase scientists» understanding of how proteins and cells function, potentially leading to more effective therapeutic drugs in the future.
An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.
These changes have an influence on the capacity of the liver and kidneys to detoxify and eliminate therapeutic drugs due to large changes in the metabolizing and transport proteins.
A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life - threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.
The identification of genes that are synthetically lethal in β - catenin - activated cancer cells would provide new targets for therapeutic drug design.
Review: New Therapeutic Drugs from Bioactive Natural Molecules: the Role of Gut Microbiota Metabolism in Neurodegenerative Diseases — Francesco Di Meo — Current Drug Metabolism
«The circadian clock regulates certain signaling pathways that are key for minimizing drug toxicity in normal tissues and increasing anticancer therapeutic drug efficacy,» said Shobhan Gaddameedhi, PhD, College of Pharmacy, Washington State University, Pullman, Washington, and senior author of this study.
We are experienced in vaccine development, therapeutic drug therapies, viral pathogenesis, small molecule administration, pharmacokinetics, and experimental surgical procedures.
We believe that leveraging human intuition through creation of a scientific game for drug discovery can not only provide a new avenue to discover therapeutic drugs for protein targets, but can also contribute to the development of new sophisticated algorithms to use in computer aided drug design.
Berkeley Lab researchers have developed a new family of nanocarriers, called «3HM,» that meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment of a deadly form of cancer known as glioblastoma multiforme.
In studies to understand the molecular basis for therapeutic drug action, he showed how tiotropium bromide (Spiriva), an inhaled drug for chronic obstructive pulmonary disease and for uncontrolled asthma, recognizes and blocks the muscarinic 3 (M3) receptor.
Charting the network of discoveries that led to the development of important therapeutic drugs, the investigators revealed that, up to now, the path to a cure has required thousands of scientists and many decades.
Most therapeutic drugs are chemically synthesized small molecules.
Therefore, this complex is a highly promising therapeutic drug target against diabetes, obesity, Wolff - Parkinson - White Syndrome, cancer, and aging.
Helmsley expanded support with an additional $ 15 million grant in 2010 to create a collaborative stem cell project involving Salk and Columbia University to fast - track the use of induced pluripotent stem cells to gain new insight into disease mechanisms and screen for novel therapeutic drugs.
Cats will be treated long - term and eventually tapered to maintenance dosages of therapeutic drug combinations.
Auburn University's College of Veterinary Medicine Clinical Pharmacology Lab offers cannabinoid therapeutic drug monitoring (TDM).
This article from 2007 indicates radio frequency identification microchips are not considered medical devices by Health Canada's Therapeutic Drugs Directorate, so there's no requirement to obtain licences for their sale or use.
Senior manager and director of pharmaceutical process chemistry, manufacturing and controls (CMC) specializing in cGMP, quality and regulatory compliance of novel small and large molecule therapeutic drugs including peptides, nucleotides, protein biologics and antibody drug conjugates (ADCs).
Senior author Dr. Santosh K. Katiyar and his colleagues wrote, «Conclusively, honokiol appears to be an attractive bioactive small molecule phytochemical for the management of head and neck cancer which can be used either alone or in combination with other available therapeutic drugs
Targeting ALK with therapeutic drugs can turn that switch back off, blocking cancer progression — at least temporarily — without harming healthy cells.
But it would, and should, cause further outcry at the banning of a non-harmful and potentially therapeutic drug, as well as at the Psychoactive Substances Act itself.
UT Southwestern Medical Center cancer researchers have identified a protein critical to the spread of deadly cancer cells and determined how it works, paving the way for potential use in diagnosis and eventually possible therapeutic drugs to halt or slow the spread of cancer.
Now researchers from North Carolina State University have updated an extensive toxicology database so that it can be used to track information about therapeutic drugs and their unintentional toxic effects.
Evaluated highly sensitive patient information pertaining to the presence of drugs of abuse through immunoassay screening on Hitachi Roche Modular Systems and monitored therapeutic drug levels utilizing a Cobas Integra 400 Plus analyzer.
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