That's an impressive claim, and it's based on newly released data from his lab that shows the ability to turn
human skin cells into liver cells.
Although no tests have yet been done on real wounds, experiments on
cultured human skin cells have been encouraging, he says.
«Our study showed that in cell culture, our materials are taken up
by human skin cells,» he added.
They grew other kinds of cells in the medium, such
as human skin cells, but these induced no such attraction in the worms.
The scientist tested their set - up using
frozen human skin cells, segments of pig heart tissue, and sections of pig arteries in volumes almost 20 times larger than previously attempted samples.
Professor Rudi Beyaert (VIB / UGent): «We found that pharmacological treatment
of human skin cells with drugs that inhibit the activity of MALT1 reduced the production of inflammation promoting proteins caused by mutant variants of CARD14.
They were created by injecting DNA derived
from human skin cells into eggs taken from cows ovaries which have had virtually all their genetic material removed.
To overcome these hurdles, Bhatia and her team
reprogrammed human skin cells into induced pluripotent stem cells (iPSCs)-- embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease.
To make Episkin, a layer of fish collagen is seeded
with human skin cells discarded from plastic surgeries.
The Hinxton Group's prediction comes in the wake of recent news that scientists at the University of Wisconsin and Kyoto University in Japan have transformed
adult human skin cells into pluripotent stem cells, the powerhouse cells that can self - replicate (perhaps indefinitely) and develop into almost any kind of cell in the body.
The successful growth of
human skin cells in culture has made it possible to restore epidermis after severe burns and other forms of damage
This research, which was performed jointly at the Roddenberry Center for Stem Cell Research at Gladstone and the Broad Center of Regeneration Medicine and Stem Cell Research at UCSF, involved using a «cocktail» of reprogramming genes and chemical compounds to
transform human skin cells into cells that resembled the endoderm.
Two teams independently discover a way to turn
ordinary human skins cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies.
To make the HSCs, the Harvard group
used human skin cells to create induced pluripotent stem cells (iPSCs), adult cells researchers genetically reprogram to an embryonic - stem - cell state, where they can grow into any kind of cell.
Using viral gene insertion and regulatory proteins, researchers turned adult
human skin cells directly into adult human blood cells, without first returning them to a fully pluripotent state.
Human skin cells grown on a flat culture remain dispersed and unable to induce the formation of hair follicles (left).
For the first time, scientists at Newcastle University, UK, have identified that the activity of a key metabolic enzyme found in the batteries of
human skin cells declines with age.
Meanwhile, Dr. Mick Bhatia's group at the Stem Cell and Cancer Research Institute at McMaster University found a way to
make human skin cells sing «Any Way... [more]
Meanwhile, Dr. Mick Bhatia's group at the Stem Cell and Cancer Research Institute at McMaster University found a way to make
human skin cells sing «Any Way You Want Me,» turning directly into blood cells without a pluripotent cell step in between.
Scientists tested cold pressed tamanu oil
on human skin cell samples, analysing wound healing factors including collagen synthesis, glycosaminoglycans, and wound closure.
Gage and Ghosh discuss
how human skin cells induced to return to an immature state («induced pluripotent stem cells» or IPS cells) are revolutionizing our understanding and treatment of mental and neurodegenerative disorders, such as Parkinson's disease, as well as leading to new models of drug development for all diseases.
Frankenbunnies Embryos made by Chinese researchers who
fused human skin cells with rabbit eggs, hoping to create a source of stem cells.
Martin Fussenegger of the Swiss Federal Institute of Technology in Zurich and his colleagues made this implant by genetically
altering human skin cells so that they would become darker in colour when exposed to rising calcium levels.
Ma used induced pluripotent stem cells to form the organs, created by rewinding ordinary
human skin cells back to a primordial, embryonic - like state.
While testing the effect of many normal, non-cancerous, human cells on the sensitivity of cancer cells to chemotherapy, they found a specific sample of
normal human skin cells that rendered pancreatic cancer cells resistant to gemcitabine.
Testing on
human skin cell lines, this study published in The Society for Investigative Dermatology, documents the action spectrum of ultraviolet damage in cells derived from both the upper layer (dermis) and lower layer (epidermis) of the skin.
Two groups of researchers report today that
washing human skin cells in similar cocktails of four genes enabled them to reprogram the cells to resemble those harvested from embryos.
Researchers at the Fund for the Replacement of Animals in Medical Experiments (FRAME) in Nottingham, have just finished the first stage of development, which draws on research showing that
human skin cells produce chemicals called cytokines when exposed to chemicals that are irritants.
Xu and his team, which includes researchers from Penn's departments of Dermatology and Biology, as well as the New Jersey Institute of Technology, started with
human skin cells called dermal fibroblasts.
Human - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously
shed human skin cells, hair and other bacteria - laden particles.
Gianneschi and his team found that the synthetic melanin nanoparticles in their experiments were not only absorbed and distributed normally by the keratinocytes in the epidermis, but they also
protected human skin cells from UV radiation damage.
Feeder cells are often used when growing
human skin cells outside the body, but physicians worry that cross-species contamination could make them unsuitable for human use.
The crux of the discovery, published online Tuesday by the journals Cell and Science, is a «direct reprogramming» technique that adds a cocktail of four genetic factors to run - of - the -
mill human skin cells.
In the Science study, led by first author Nan Cao, PhD, a postdoctoral fellow in Ding's lab, the researchers used a cocktail of nine chemicals to
change human skin cells into beating heart cells.
The goal was to analyse the changes in minimal erythritol dose (MED), which is the lowest concentration of UVB radiation required in order to mutate and
damage human skin cells.
Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF) have successfully
converted human skin cells into fully - functional pancreatic cells.
2007 Yamanaka and Thomson succeed in reprogramming
adult human skin cells into induced pluripotent stem cells.