Sentences with word «aberrant»

The word "aberrant" means something or someone that is abnormal, deviating from what is considered normal or usual. Full definition
Freud sees every psychiatric problem as a manifestation of sexual issues, while Jung believes that doctors should get at whatever the root causes of aberrant behavior prove to be.
Vigilant monitoring of aberrant behavior such as early refill requests, treatment noncompliance, and reports of lost or stolen prescriptions will improve the recognition of signs of abuse.»
Anaplastic lymphoma kinase (ALK)-- positive anaplastic large cell lymphoma (ALCL) frequently carries the t (2; 5)(p23; q35) resulting in aberrant expression of chimeric nucleophosmin - ALK.
To acquire new insights into the biology and possible therapy of these tumors, Feigin et al. looked for aberrant expression of G protein — coupled receptors, cell signaling proteins that have been successfully targeted for treatment of other disorders such as depression.
Therefore, miR - 142, a miRNA frequently upregulated in human BCSCs than in the NTG cells (Shimono et al., 2009), could provide at least a part of the shared molecular mechanism for aberrant activation of the canonical WNT signaling pathway in BCSCs and for the initiation and progression of breast cancers.
These initial results are so promising that complete thyroid diagnostic profiling and treatment with thyroid supplement, where indicated, is warranted for all cases presenting with aberrant behavior.
Vibrational + Contains astragalus root, a powerful adaptogenic herb that heightens immune system responses and lengthens telomeres in healthy cells, * but not in aberrant cells.
Targeted drugs bind and shut down the activity of aberrant proteins - products of specific mutations.
A hallmark of the Notch pathway is its gene dosage sensitivity, such that small differences in the amount of Notch activity can cause aberrant cell fate choices and T - cell leukemia.
It may be that a disease forms aberrant patterns, and those patterns lead to the psychosis.
As aberrant as his behavior may be, he's not the strangler.
Moreover, the autoimmune protocol addresses many of the underlying root causes of aberrant immune responses.
Several factors newly discovered to be phosphorylated by GSK - 3 are also known to be mutated in acute myeloid leukemia, a condition in which aberrant splicing causes uncontrolled white blood cell proliferation.
Spotlight shines light on an institution that has persisted in aberrant behaviour for almost two milenia.
The completion of differentiation correlated with less aberrant methylation during the reprogramming process.
The goal is NAC supplementation sufficient to increase glutathione levels, prevent aberrant insulin signaling, and restore night - time mitophagic activity and amino acid homeostasis to a youthful level.
In addition to being integral to cell biology, tyrosine kinases also present targets for new anticancer therapies: One of the most highly touted, rationally designed anticancer compounds, Gleevec, inhibits an oncogenic tyrosine kinase whose aberrant activity fuels the rampant growth of cells in patients with chronic myeloid leukemia.
Transformed cells such as the Jurkat line may show aberrant DNA methylation patterns at specific loci [57], possibly complicating analyses of cytosine methylation and HIV - 1 latency.
Reddy BS, Hamid R, Rao CV Effect of dietary oligo fructose and inulin on colonic pre-neoplastic aberrant crypt foci inhibition.
MPAA Rated: Not rated, but originally NC - 17 for aberrant sexual content, explicit dialogue, disturbing thematic material, violence, and drug content Running Time: 134 min.
«We identified the cytosolic protein Vms1 as a key component of a novel pathway termed mitoRQC that protects mitochondria from the toxic effects of such aberrant proteins,» explain the authors of the study.
Section of a stomach cancer (seen under a microscope) showing aberrant expression of YBX1 protein (stained brown).
Ghosh and Chattarji's new findings explain how aberrant electrical signaling in individual neurons can add up to give rise to amygdala hyperactivity and generalization of fear in PTSD.
«It is our hope that further understanding of the complex network of enzyme and cofactor interactions controlling heme synthesis will continue to contribute ideas for therapeutic strategies to treat diseases caused by aberrant regulation of heme metabolism,» the authors write.
lentiviral vectors contain a deletion in the 3» LTR that prevents aberrant activation of nearby genes.
29) Chari R, Coe BP, Vucic EA, Lockwood WW, Lam WW (2010) An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer.
I've seen how all the various forms of trauma affect the attachment system, and I've worked with restoring the normal - range and healthy attachment system of children who's attachment networks have been damaged by trauma from aberrant parental behavior — profound neglect, physical abuse, sexual abuse.
In collaboration with Dr. Ke Xu's lab at UC Berkeley, the team determined that this is because of aberrant accumulation and distribution of Ankyrin - G in the AIS.
Christianson said his team uses neuroscience techniques «to investigate the biological basis for social cognition with the hope that we can better understand and treat people with conditions marked by aberrant social cognition such as autism or schizophrenia.»
This provides clients a rapid and economical first insight regarding general health and potential aberrant pathways for their mouse model.
But what can you expect, as aberrant growths die and break down, attempting to move through your organs of elimination?
Knockdown of dynamin - binding protein or Tuba results in abnormal kidney development and other aberrant phenotypes in zebrafish models (middle and right panels) compared with controls (left panel).
Aberrant migration into different organs, including the CNS, has been described in cats.
It's a cosy basement venue but the gallery's founders — aberrant architecture and Beatrice Galilee — have big plans for it.
MPAA Rating: (for pervasive sexual and crude content including aberrant sexuality, strong language and some drug material)
By combining in vivo labeling, confocal microscopy and electrophysiological recordings, we identified an Aβ - induced aberrant neuronal network as the primary mechanism.
The pet denialists we gain from such tolerance vary greatly in their stance on AGW and their attitude to RealClimate but do share an inability to take on - board any evidence that they find contrary to their own aberrant views on AGW.
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