Sentences with phrase «affected cells»

Such editing affects all cells in the developing organism and passes those changes down to future generations.

For example, in cancer treatment, inhibitors are used to stop the division of affected cells, thus slowing the disease's progression.

Other studies show that visceral obesity raises a person's risk of developing colon cancer, perhaps because it increases circulating levels of hormones that affect cell growth.

This can affect cell function, leading to mutations and even cell death.

Recent studies show self - induced changes in mood can increase serotonin production, positively affecting cell signaling in the body (4).

The editing techniques would likely affect each cell differently, so that the resulting embryo would be a mosaic of cells with different genetic alterations.

I'm studying how changes in chromosome number affect cell physiology and cancer progression.

This allows researchers to randomly screen the entire genome for genes that affect cell survival.

But biologists still don't know what thousands of proteins do, and how their presence or absence affects the cell.

How these bugs affect our cells is a key part of these processes.

For a long time, however, exactly how gravity affects the cells remained a mystery.

Major brain disorders such as PD, ADHD, and schizophrenia are related to abnormalities affecting these cells.

Vitamin D needs to be present at sufficient levels in the cell in order for the thyroid hormone to actually affect that cell.

This remarkable gland in the neck affects every cell in your body, regulating cell metabolism like a thermostat.

The hormones produced by your thyroid gland affect every cell and all organs of the body, and are predominantly responsible for the regulation of metabolism.

Understanding how inflammation affects the cell and the way to down - regulate it is essential to heal most any condition.

The fats that a dog consumes affect every cell in their body, especially the cells in their brain and eyes.

But the molecules also affect the cells of the animal ingesting the food, by damaging the DNA, proteins, and other critical parts of the cells in their body.

Based on analyses of over 600 drug and breast cancer cell pairings, researchers showed that, for some cells, drug exposure can cause significant changes in gene expression — indicating the successful action of a drug on its target — without affecting cell growth or survival.

Sugar causes inflammation, which affects every cell in your body.

Depletion of ABL kinases did not affect cell growth in monolayers or colony formation in Matrigel (fig.

In addition, disruption frequency in cultures treated with X4 - ZFNs as determined by deep sequencing remained remarkably stable between 32 — 33 % from day 5 to day 26 post-transduction in the absence of HIV, which suggests that simultaneous disruption of ccr5 and cxcr4 does not adversely affect cell growth.

OPTN may constitute a cellular target for adenovirus E3 14.7, an inhibitor of TNF - alpha functions, thereby affecting cell death.

Systems biology uses a variety of omics tools including genomics, bioinformatics, metabolomics and proteomics to understand biology at a high level of complexity, such as how mutation or loss of a single gene affects cells, tissues and even the entire organism.

In the past few years, we have developed other tools to control the cell micro-environment (micro-channels, confiners etc) and we have exploited them to understand how mechanical constrains affect cell division and migration.

ANXA1 affects cell proliferation, invasion and epithelial - mesenchymal transition of oral squamous cell carcinoma.

It arises from mutations affecting cells, called melanocytes, that produce the pigment melanin, which gives color to those body parts.

Recently, though, scientists have studied how chlorine affects the cell walls of «gram - negative» bacteria, organisms including those causing typhoid fever, dysentery, cholera and Legionnaires» disease

Proteins in the cytoplasm form a highly structured yet changeable matrix affecting cell shape, division and motion, and the transport of vesicles and organelles.

Importantly, the ligands impaired myofibroblast function without affecting cell viability.

«New mechanism affecting cell migration found.»

These immature cells were impaired at turning into mature, specialized cells called cortical neurons — the most affected cell type in frontotemporal dementia.

In addition to our computational work, we run a small wetlab where we use CRISPR - Cas genome editing in human cell lines to obtain a deeper understanding of how genetic variants affect the cell.

Each of these forms of cancer usually affects the cell linings of the lungs, and / or the abdominal cavity and the heart.

«We hope this technique will be used widely in the field, and that it will ultimately bring more clarity to how these drugs affect cells — and how we can get them to the right locations in the body.»

In fact, preliminary evidence already exists that HHV - 6 may be associated with some lymphomas, a diverse set of cancers affecting the cells of the immune system.

This molecule affects the cells of pulmonary blood vessels, which respond to PTHLH by triggering remodelling processes.

Petroleum / Petrolatum / Paraffin / Mineral Oil — Found in various products from lipsticks to moisturizers this is a petrochemical that affects cell development and results in premature aging.

Charlie inherited the faulty RRM2B gene from his parents, affecting the cells responsible for energy production and respiration and leaving him unable to move or breathe without a ventilator.

Researchers then tested cell cultures and mouse models by using a gene editing process called CRISPR - Cas9 to demonstrate how the presence or absence of myomaker and myomerger — both individually and in unison — affect cell fusion and muscle formation.

Dengue infection, which mainly affects cells in the blood, can lead to neurological complications.

Tasoglu and Demirci also demonstrated that micro-robotic construction of cell - encapsulating hydrogels can be performed without affecting cell vitality and proliferation.

The group then ran dozens of microscopy tests with Dan Wagner, Rice associate professor of biochemistry and cell biology, to see how different formulations and amounts of biochar affected cell signaling.

I am also characterizing mechanical properties of hydrogels and observing how changing these properties affects the cell's biological response.

Friis, a postdoctoral fellow in Mike Schultz's biochemistry lab, examined how dietary changes at the cell level can affect cell health.

They found that KIF1B - β affects the cells» power stations, the mitochondria, by activating an enzyme named calcineurin.