Sentences with phrase «kidney cells»
"Kidney cells" refers to the specialized cells in our kidneys, which are the organs responsible for filtering waste and producing urine in our bodies. Full definition
But the study their claim is based on is an in vitro trial in kidney cells.
onnit.com
He found a way to transform certain types of human stem cells into kidney cells.
This binding causes kidney cells to change their structure and function, permitting disease onset.
As kidney failure progresses, more kidney cells die because of poor blood supply due to dehydration and continued injury.
The discovery is the culmination of six years of work in the lab, assembling various genes that are important for making kidney cells.
Current research supports antioxidant intake as an effective means of promoting kidney cell health.
Our research has shown it to be non-toxic on sensitive kidney cells, even at high usage.
If enough functional kidney cells remain, they may be able to adequately meet the body's needs for waste removal.
Over time, kidney cells die and are replaced by scar tissue.
293 is a human embryonic kidney cell line, and 293T is a derivative of 293 cells with an expression of SV40 T antigen.
First, HIV and SIV do not grow in monkey kidney cells.
«Massive single - cell survey of kidney cell types reveals new paths to disease: Study of over 57,000 cells from mouse kidneys help identify human renal disorders.»
One, FLUCELVAX, is grown in canine kidney cells, and the second, Flublok, is grown in insect cells.)
Seroneutralisation on puppy kidney cell cultures (collection in dry tube (no anticoagulant) of two samples of the mother's serum at 10 - 15 day interval, the first sample being collected in the days following abortion or stillbirths).
Thus, upon activation by ActD, AKT becomes an inducer of p53 tumor suppression instead of being a survival factor, as consistently shown in human embryonic kidney cell lines (293 and 293T), human hepatoma cell line (HepG2), and mouse hepatoma cell line (Hepa - 1c1c7).
If not for the polio vaccine, which was developed from human fetal kidney cells in the 1950s, UNICEF estimates that polio would kill 640,000 people every year.
In observing kidney cells from the FAN1 knockout mice, the researchers noticed that their nuclei were abnormally large.
«Hydroxyethyl starch has direct harmful effects on kidney cells, lab study finds.»
«Nephrologists are trained to evaluate a constellation of factors in determining whether or not a patient has a condition that may temporarily affect kidney function, such as dehydration or heart failure, and to distinguish these temporary conditions from true kidney cell damage,» said Dr. Barasch, one of the authors of the study.
An initial drug test suggested that the virus manipulates the cell's internal skeleton, so the team stained the skeleton and videotaped the viral assault on a live kidney cell of a green African monkey.
In addition, monkeys» kidney cells do not normally support the growth of HIV.
AFRICAN GREEN MONKEY CELL: An African green monkey kidney cell expressing the gene c - src, imaged using Bessel beam plane illumination.
To find out, the team engineered baby hamster kidney cells to express the human ACE2 receptor.
«iPS - derived kidney cells successfully connected to capillary network.»
The study, led by Katalin Susztak, MD, PhD, a professor of Renal - Electrolyte and Hypertension and Genetics, also identified three novel cell populations, along with all previously described kidney cell types.
Paolo Fiorina, MD, PhD (Boston Children's Hospital / Harvard Medical School) and his colleagues have discovered that a receptor called B7 - 1 is expressed by kidney cells during the progression of diabetic nephropathy.
Dunsby and colleagues used it to measure glucose uptake, indicated by a fluorescent biosensor, in multicellular kidney cell spheroids.
Through the ureter, they fed kidney cells from newborn rats, re-coating the labyrinthine tubules and ducts that make up the kidney's urine filtration system.
In 2015 the Church lab announced it had CRISPR'd out 62 PERV genes in pig kidney cells growing in lab dishes.
The scientists in London got the same result in a similar experiment using mammalian kidney cells, showing that healthy and mutant cells compete directly against each other in mammals.
Scientists at Bayer made an artificial version of the human gene that manufactures factor 8 and inserted it into kidney cells taken from baby hamsters.
By blocking kidney cells» expression of a gene that is critically involved in the circadian clock system, the team found that the clock is responsible for the temporal adaptation of kidney function to the light and dark phases of the day that correspond to activity and rest.
Obesity suppresses an important cellular process that prevents kidney cell damage, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
Normal - weight mice with kidney disease and defective autophagy (due to a gene deletion) also experienced kidney cell damage.
However, in obese mice with kidney disease, autophagy was suppressed and kidney cells became damaged.
They found that reducing the level of VEGF - A in mouse kidney cells caused kidney failure very similar to that seen in women suffering from preeclampsia.
The human kidney cell involved survived the experience, and though we are a long way from the laser eyes of Cyclops from the X-Men franchise, the achievement suggests that «living lasers» might be created inside live animals.
The majority of kidney cell carcinomas are missing the VHL tumor - suppressor gene.
In those cases, the NPCs often matured into adult kidney cells in a manner of days, leaving no steady population of progenitor cells to study.
«We provide a proof - of - principle for how to make and maintain unlimited numbers of precursor kidney cells,» says Juan Carlos Izpisua Belmonte, professor in Salk's Gene Expression Laboratory.
Such early - stage kidney cells could be used to grow replacement kidney tissue in order to study the organ as well as treat disease.
To upgrade their DNA «switches,» Wong and his colleagues steered clear of transcription factors and instead switched human kidney cell genes on and off using scissorlike enzymes that selectively cut out snippets of DNA.
The basic approach is to implant a polymer matrix filled with genetically altered kidney cells that build antiangiogenesis proteins.
Reporting in Science, a team led by researchers from the Broad Institute of MIT and Harvard, Brigham and Women's Hospital, and Harvard Medical School describes a new approach to prevent death in these essential kidney cells.
In the Nature Communications study, UTSW researchers also reported how miR - 17 causes cyst proliferation: the molecule essentially reprograms the metabolism of kidney cells so that cellular structures called mitochondria use less nutrients, freeing up resources to instead make cell parts that become cysts.
An alternative possibility is that successful propagation of TMAdV may depend on infection of a specific host cell type, such as A549 lung, and not BSC - 1 or PMK kidney cells.
The scientists got another surprise when they followed up on this finding with mouse experiments that exposed specialized kidney cells called «podocytes», a key component of the blood filtering, to high levels of glucose.
Similar results were obtained when the toxicity of niclosamide and oxyclozanide were evaluated against HEK293 human embryonic kidney cells [35, 36].
Our chemically modified siRNA molecules, designed to retain stability in the bloodstream without stimulating the immune system, are able to target certain kidney cells without the need for a delivery system when given intravenously.