Sentences with phrase «model for human disease»

Historically, researchers have generated their own lines of knockout mice to serve as models for human disease, such as heart disease or cancer.

No doubt, knowledge of the mouse genome will help scientists design more effective mouse models for human disease and disorder.

The emphasis is on developing intellectual abilities and research skills through investigations of infectious diseases of food - producing, companion, and aquatic animals, as well as animal models for human disease.

This research is all aimed at tissue repair strategies, but it also may provide new in vitro models for human disease.

Cats and dogs that develop diseases like cancer naturally are often better models for human disease than lab rodents are, which is why more and more drug...

But Franklin and others suspect that in their zeal to clean up, facilities may have wiped out some of the microbial complexity that makes mice useful models for human disease.

The mouse makes an excellent model for human disease because the organization of their DNA and their gene expression is similar to humans, with ninety - eight percent of human genes having a comparable gene in the mouse.

And the enrichments may make the animals better at what they do: serving as important models for human disease.

«Previous studies of cardiac microtissues primarily used harvested rat cardiomyocytes, which is an imperfect model for human disease.»

The research group that Cecilia Johansson works in specializes in using dog as a comparative model for human disease.

Hennebold is attempting to create these «knockout» models for human diseases like hereditary blindness and deafness, among other disorders.

These mice will be preserved in repositories and made available to the scientific community representing a valuable resource for basic scientific research as well as generating new models for human diseases.

«Ultimately, we have to get a human model for human diseases so that we can expand human experimental biology in an ethical way and ensure that better, safer drugs get to patients faster,» he says.

He later combined it with studies on chromatin, tissue specific gene expression and mouse models for human diseases including Type II diabetes, polycystic kidney disease as well as cancer.

Reprogramming human somatic cells to pluripotency represents a valuable resource for the development of in vitro based models for human disease and holds tremendous potential for deriving patient - specific pluripotent stem cells.

«Of mice and men — are mice relevant models for human disease?»

The exception is when an animal is itself the laboratory model for a human disease, and that is not the case with FIP.

It now looks like many of these traits could be controlled by the combination of genes between different strains, thus producing mice that are better models for human disease.»

It's also what makes them useful models for human disease,» she said.

Mice hold a very important place as models for human diseases, including cancer, in biomedical research.

Goal: Characterisation of mouse models for human diseases to understand molecular mechanisms of human disorders and for the development of new therapies

By mapping candidate single nucleotide polymorphisms (SNPs) and performing detailed functional analyses, they show that mutations in the Wilson disease gene ATP7B are associated with copper accumulation in the liver, validating the use of these dogs as a model for the human disease.

Not only can organoids potentially offer a better model for human disease, they can also be surprisingly easy to coax into being.

Human medical research by physicians and scientists using the greyhound as a model for human disease.

Exciting gene therapy research aimed at correcting this condition (in dogs as a model for human disease) is currenty being conducted at the University of Pennsylvania.