Sentences with phrase «novel therapies»

The researchers also hope to test gene therapy in larger animals, and plan to develop novel therapies for other forms of genetic hearing loss.

Using genetically engineered mice as disease models, my laboratory is interested in studying complement activation and regulation in these disease states, thus eventually developing novel therapies.

This discovery forms the basis of novel therapies for the prevention and treatment of colon cancer.

These experiments are innovative because they seek to improve a mouse model based on current knowledge from human disease, while also testing novel therapies that could be of benefit for affected individuals.

The development of new and effective cancer treatment requires the translation of basic laboratory discoveries into novel therapies that can be tested in patients.

The other novel therapies that are being studied are also at the very early stages.

His research interests include novel therapies for lung cancer treatment and prevention.

In the future, epigenetic editing could also be used to design novel therapies by initiating permanent changes to cell biology.

Techniques like that may lead to novel therapies while avoiding the primary downfall of stem cell therapies: the development of tumors.

This will significantly accelerate the rate of scientific discovery and the development of novel therapies.

His research is also focused on reducing short - and long - term effects of treatment in pediatric ALL patients, as well as testing novel therapies in patients with relapsed disease.

Dr. Xin - Yun Lu, an established investigator pursuing the potential of two fat - cell derived hormones as novel therapies for depression and PTSD, has been named professor in the Department of...

September 18, 2013 NIH awards University of Chicago $ 1.5 million to study novel therapy for multiple sclerosis Researchers from the University of Chicago have been awarded a five - year, $ 1.5 million grant from the National Institutes of Health (NIH) to develop stimulated dendritic cell - derived exosomes that show remarkable promise as a treatment for multiple sclerosis and other neurological diseases involving loss of myelin, the insulation around nerve fibers.

Furthermore, these mice would provide an excellent model to test novel therapies aimed at preventing metastasis.

«Our goal is to build a science - focused company that discovers novel therapies for heart failure patients.»

With more than 18 years of experience in drug discovery working on molecular mechanisms underlying monogenic and multigenic metabolic and fibrotic disorders as well as hematologic malignancies, Dr. Martini's laboratory is focused on identifying novel therapies and applying translational approaches for drug development in rare genetic disorders.

«Sepsis: New, novel therapy proposed by researchers.»

In addition, the FDA will continue to work closely with industry to find other ways to aid in the effort to bring novel therapies to patients as quickly, and as safely, as possible.

Scientists at the Gladstone Institutes are pursuing novel therapies to stop this cacophony in the brain with the goal of treating epilepsy, as well as seizure activity resulting from traumatic brain injury, stroke, or Alzheimer's disease.

«The region - specific cells we found could provide tremendous advantages in the laboratory to study development, evolution and disease, and may offer avenues for generating novel therapies,» says Salk Professor Juan Carlos Izpisua Belmonte, senior author of the paper and holder of Salk's Roger Guillemin Chair.

Currently, we are studying several novel therapies with unique mechanisms of actions, including small molecules, monoclonal antibodies, and immunotoxins.

Overmyer's expertise as a technologist is bolstering research with Peter Muir, the Melita Grunow Family Professor in the School of Veterinary Medicine at UW - Madison, who is using canine models for osteoarthritis, and with Peter G. Shultz at the Scripps Research Institute who is investigating novel therapies in humans.

Using in vitro cell culture and an in vivo colorectal cancer mouse xenograft models, the laboratory is studying novel therapy combinations and interventions to help increase tumor response to treatment.

The Company develops and markets novel therapies, based on neurostimulation and digital medicine, for chronic health conditions.

Meanwhile, his research teams are moving several other novel therapies toward clinical trials, each of which has potential for use in the synergistic model of cancer treatment that Black believes will offer the best hope for his patients.

The clinical trial results, published online in the Journal of Allergy and Clinical Immunology: In Practice, suggest that Verapamil represents a promising novel therapy for the treatment of CRS with nasal polyps.

Other areas of research include designing novel therapies based on molecular pathways and identifying predictive biomarkers in patients to design personalized, targeted therapies.

«New brain map could enable novel therapies for autism, Huntington's disease: Brain connectivity atlas assists in the understanding of mental, neural disorders.»

We will next consider the methods available to analyze biological networks, demonstrate the application of these principles to selected problems in biology and medicine, and discuss the implications of biological network theory as a construct for characterizing human disease and defining novel therapies.

With these variations to enlist CRISPR gene - editing technologies, we can quickly engineer mouse models to carry the same mutations present in patients with specific genetic diseases, and use them as pre-clinical models for developing and validating novel therapies.

Finally, Pollard wants to close the loop by incorporating code - writing approaches, such as genome editing using CRISPR - based approaches and synthetic biology, which are needed to test and validate hypotheses and could also provide novel therapies.

Gladstone was a great fit for me, especially with its background in developmental and translational biology and Bruce's research focus on cutting - edge technologies to model genetic disease and find novel therapies for treating them.

A U.S. biotech company will attempt to resurrect 20 brain - dead patients by a combination of novel therapies involving brain stem cells.

Professor Ferner's research with national and international collaborators focuses on defining clinical phenotype in the neurofibromatoses, determining the natural history of optic pathway glioma and developing robust clinical and patient centred outcome measures for monitoring novel therapies.

«There is an urgent and ongoing need for the development of novel therapies which efficiently target triple - negative breast cancers,» Meyers said.

The recent EMBO conference Towards Novel Therapies: Emerging insights from structural and molecular...

The two tests are also being considered for inclusion in a multicenter study of pediatric malignancies led by Dana Farber Cancer Institute (The Genomic Assessment Informs Novel Therapy (GAIN) Consortium Individualized Cancer Therapy 2, iCat2 Study).

«Therefore, any potential promising results get diluted because novel therapies are not administered to those select patients who are most likely to respond, based on their tumors» molecular profile.

An impressive patient account exemplified how novel therapies developed using animal models improve human health and saves lives.

Comprehensive clinical trials, especially basket and umbrella platforms, are needed to efficiently evaluate emerging novel therapies that will hopefully lead to faster approval of better treatments for people with cancer around the world.

Novel therapies such as gene therapy represent an opportunity to fix the faulty gene responsible and allow these children the chance to have a normal life.

The Company's transformative gene repair technology presents a promising opportunity to create novel therapies that address the significant unmet need in the treatment of serious genetic neuromuscular diseases.

Further, 25 percent of patients went on to receive a study recommended novel therapy, which resulted in 10 percent of patients achieving a partial or complete remission lasting six month or longer.

[2] New areas of cancer research around novel therapies like the ketogenic diet, oxygen therapy (HBOT), and insulin potentiation therapy (IPT) offer promising ways to tackle cancer alongside traditional cancer treatments.

Dog Studies CANCER Novel Therapies Common heart medications as an effective adjunct therapy for dogs with hemangiosarcoma, an aggressive and deadly cancer.

Munich, Germany About Blog Definiens mission is to accelerate breakthroughs for this approach by helping scientists leverage Tissue Phenomics to deepen understanding of disease biology and immune system mechanisms, to bring multi-omics data into a cancer - relevant context, and to facilitate the translation of new insights into novel therapies and treatment strategies.

CAMBRIDGE, Mass., Nov. 16, 2016 — Proclara Biosciences, a biotechnology company developing novel therapies for diseases caused by protein misfolding, today announced that the U.S. Patent and Trademark Office has issued two new patents related to the company's proprietary General Amyloid Interaction Motif (GAIM) platform.

These mouse models are accelerating the development of novel therapies in HIV infection and oncology.

It includes the Rheumatology Clinical Research Unit, which currently is conducting clinical trials of novel therapies for lupus, rheumatoid arthritis, IgG4 - related systemic disease and osteoarthritis.

I - Stem, the Institute for Stem cell Therapy and Exploration of Monogenic Diseases, has signed an agreement with Swissbased healthcare company Roche to use I - Stem's technologies in discovering novel therapies to treat devastating central nervous system (CNS) diseases such as Alzheimer's, schizophrenia, depression and anxiety.