Sentences with phrase «on cancer cells»

So the most commonly consumed vegetables in Western countries had very little effect on cancer cell growth.

The targeted viruses «have the potential to add a new tool to our arsenal,» he says, because they home in on cancer cells more aggressively.

Historically, a potential therapeutic compound would be tested on cancer cell lines to validate the functional efficacy of the compound.

Much of what we know about cancer and many modern medicines that treat it grow from experiments on cancer cells.

A second hurdle in cancer is to generate an immune response sharply focused on cancer cells while avoiding normal cells and tissues.

The removal of these components might be expected to unleash an assault by the immune system on cancer cells left after surgery.

The same seems to be true of the gene switches that turn on cancer cells.

Among patients who have this type of lung cancer, nearly one in three will carry a particular genetic mutation on their cancer cells.

The demands of rapid cell division put a strain on cancer cells, and the approach works by tipping cell stress over the edge.

These antibodies can identify substances on cancer cells or normal substances that may help cancer cells grow.

Researchers can also find information on the cancer cell lines that are most suitable for their experiments.

As a result, chemotherapy agents have a greater impact on cancer cells since they target rapidly dividing cells.

Since these experiments were only performed on cancer cells in test tubes, the researchers took the next step and ran tests on breast cancer tumors in live mice.

This ability to isolate, culture and grow the cancer cells will allow researchers to zero in on the cancer cells that matter to the health of the patient.

The experiments on cancer cells were «thoroughly conducted and state of the art,» he adds.

The medicines, which help unleash the immune system on cancer cells, were tested in patients with advanced lung cancer.

Effective combination therapies rely on the synergies between the stimulation of the immune system by immunotherapies and direct attacks on cancer cells by other therapies.

Triple negative breast cancers are those that do not have estrogen or progesterone receptors, and do not have an excess of the HER2 protein on the cancer cell surfaces.

In this study, the SIgN team discovered for the first time that the integrity of p53 affects the production of a special cell surface protein called Major Histocompatibility Complex (MHC) class I. MHC class I molecules on the cancer cell surface serve as targets for the immune system.

Some of them come from studies on cancer cells, which can blunt the immune system.

It was also found to reduce growth receptors on cancer cells so that cancer cells could not grow.in response to chemicals that stimulate cancer cell production.

In CAR - T therapies now used in humans, some of the patient's own immune cells are removed, engineered to attack a surface antigen on the cancer cells, and returned to the patient's body, where they target the cancer cells for destruction.

In the early 1990s, in vitro tests on cancer cells by Lane and his colleagues hinted that some compounds could restore mutant p53's normal function.

Killing Cancer From The Inside: Three new studies suggest ways to home in on cancer cells during treatment, leaving surrounding healthy tissue unharmed.

New biological mechanisms were uncovered by the study, including the observation that the injected macrophages which accumulate in the tumor stop engorging on cancer cells after about a week.

But then, in 2006, researchers in Canada working with breast - cancer cells found that metformin increased the activity of an enzyme involved in tumor suppression, suggesting that the drug might fight cancer by working directly on cancer cells.

«Purple sweet potatoes have been shown to have better cancer - fighting abilities, with a positive effect on cancer cell growth,» Flores said.

Once Herceptin binds to HER2, however, DM1 is released and acts on cancer cells in the vicinity.

Stress - surveillance contributes to anti-neoplastic immunity through the activation, on lymphocytes, of the NKG2D receptor that recognizes ligands (NKG2D - L) expressed on cancer cells.

We target tumours by exploring how the proteins found on the cancer cell surface can be utilised to inhibit growth or kill tumours.

It's a type of cancer immunotherapy, which harnesses the body's immune system to take on cancer cells.

He also investigates the effects of 2HG inhibitors on cancer cells.

«Based on our findings, we speculate that SapC - DOPS could have a synergistic effect when combined with chemotherapy or radiation therapy, both of which are known to increase the levels of exposed PtdSer on cancer cells,» Kaur says.

Telomeres» partner in crime is the enzyme telomerase, which helps keep telomeres long and healthy, a property that's made it the subject of almost science - fictional fascination: it confers immortality on cancer cells and, in a landmark 2010 study, reversed the aging of telomerase - deficient rats.

Similar strategies already in use select immune cells that recognize any cancer antigen, but Swanton's group would select those that are primed to recognize the trunk antigens that occur on all cancer cells.

After completing her graduate studies in 2006, she joined the laboratory of Dr. Craig B. Thompson at the University of Pennsylvania for postdoctoral work focusing on cancer cell metabolism.

«We developed a technique that targets lipid rafts on cancer cell membranes,» says Professor Ye Zhang from OIST's Bioinspired Soft Matter Unit, who led the research.

It also focuses more narrowly on cancer cells, so that far fewer healthy cells are killed,» she says.

The ManCou multicolored fluorescent probe glows different colors and different intensities depending on a cancer cell's type and malignancy.

In collaboration with investigators from the University of Copenhagen and University of Chicago, the researchers developed novel CAR T cells that express a monoclonal antibody called 5E5, which specifically recognizes a sugar modification — the Tn glycan on the mucin 1 (MUC1) protein — that is absent on normal cells but abundant specifically on cancer cells.

The more it's expressed only on cancer cells, the more targeted the therapy becomes,» says Colin Weekes, MD, PhD, CU Cancer Center investigator and assistant professor in the Division of Oncology at the CU School of Medicine.

Co-senior author on the Cancer Cell study, Dr. Matthew Wilkerson, associate professor and Bioinformatics Director of The American Genome Center and the Collaborative Health Initiative Research Program at the Uniformed Services University.

A new study by a Cornell University researcher found this coating is especially thick and pronounced on cancer cells and is a crucial determinant of the cell's survival.

«The LINK - A dependent HIF1 signalizing cascade and the consequent effects on cancer cells implicate LINK - A and LINK - A interacting kinases and receptors as promising therapeutic targets for TNBC.»

Antibody that blocks a «do not eat» flag on cancer cells turns the immune system against all tumor types

The researchers found that long glycoprotein chains on a cancer cell's surface cause the cell membrane to push away from its environment and bend inward.

By contrast, the neoantigen vaccine is custom - made for each patient using antigens produced by mutations unique to the patient's cancer and only present on cancer cells, thus bypassing the nature immune tolerance process.

Radiation treatment, also known as radiotherapy, destroys cancer by focusing high - energy rays on the cancer cells.