Sentences with phrase «progenitor cells»
Progenitor cells are a special kind of cells in our body that have the ability to develop into different types of cells. They act as building blocks, giving rise to more specific cells that make up tissues and organs. Think of them as cells with potential, like the ingredients that can turn into various dishes when cooking. Progenitor cells play a crucial role in the growth, repair, and maintenance of our body. Full definition
Cortical neural progenitor cells in turn give rise to immature neurons.
sciencedaily.com
Recent evidence suggests the existence of progenitor cells in adult tissues that are capable of differentiating into vascular structures as well as into all hematopoietic cell lineages.
Individual neural progenitor cells in culture produce different neuron types as time goes by, starting with the innermost cells (green) and followed by more superficial neurons (red).
ViaCyte's product candidates are based on the derivation of pancreatic progenitor cells from stem cells, which are then implanted in a durable and retrievable cell delivery device.
Review of «Antitumor Effects of CD40 Ligand - Expressing Endothelial Progenitor Cells Derived From Human Induced Pluripotent Stem Cells in a Metastatic Breast Cancer Model» from Stem Cells TM by Stuart P. Atkinson.
In the CNS, transplanted human neural progenitor cells derived from prenatal cortex (hNPCctx) display characteristics important for cell - based rescue of degenerating neurons.
Asterias has banks of these embryonic stem cells, derived from this cell line, which the company can multiply to make cells as needed and, in turn, convert them into oligodendrocyte progenitor cells for use in clinical trial evaluation in patients.
This is an immunostaining after two weeks of differentiation of neural progenitor cells into neurons.
Delayed cell injection of allogenic mesenchymal progenitor cells for bone regeneration in an ovine critical - sized segmental tibial bone defect.
«We isolated kidney progenitor cells from mice and searched for the most favorable culture conditions,» said Assistant Professor Shunsuke Tanigawa of Kumamoto University.
Encouragingly, a population of cardiac progenitor cells derived from endogenous cardiospheres (eCS) can differentiate into cardiomyocytes in vivo [1, 2] and may represent an enhanced stem cell strategy for myocardial regeneration.
Arap W and Pasqualini R Engineered embryonic endothelial progenitor cells as therapeutic Trojan horses.
It's blood in a newborn baby's umbilical cord that's rich in a type of stem cell called hematopoietic progenitor cells (HPCs).
The product combines pancreatic progenitor cells called PEC - 01, produced by a directed differentiation process, encapsulated with a semi-permeable device called the Encaptra ® Drug Delivery System, both are proprietary technologies.
Instead of starting with embryonic stem cells, as Astellas does, several other research groups are working with retinal progenitor cells found in the eye.
Osteogenic differentiation of mesenchymal progenitor cells in computer designed fibrin - polymer - ceramic scaffolds manufactured by fused deposition modeling.
AST - OPC1, an oligodendrocyte progenitor cell population derived from human embryonic stem cells, has been shown in preclinical testing in animals and in vitro to have three potentially reparative functions that address the complex pathologies observed in demyelination disorders, such as spinal cord injuries, and multiple neurodegenerative diseases, including multiple sclerosis and white matter stroke.
Seldon's San Francisco - based company, Finless Foods, is using cellular agriculture to grow fish in a lab, using progenitor cells taken from a small piece of fish meat.
They demonstrated how ANG stimulates proliferation of myeloid progenitor cells.
The researchers used mouse progenitor cells lacking PU.1 to explore this mystery.
«We've found that these Gli1 progenitor cells differentiate into myofibroblasts, and in fibrotic disease, when they are ablated, we can rescue organs and organ function,» said Humphreys.
Glomeruli filter the blood to make urine, and both the glomeruli and the tubules are generated from kidney progenitor cells during fetal life.
Holoclones express high levels of stem and progenitor cell markers CD44, α2β1 integrin, and β - catenin.
Complete obliteration of bone marrow progenitor cells by chemotherapy or bone marrow cancer can result in bone marrow failure and death.
Starting with transplants of human oligodendrocytes in the late 1980s [40], and more recently with populations of human oligodendrocyte progenitor cells isolated from the developing or adult CNS, or from human embryonic stem cells, it has been possible to generate extensive myelination upon transplantation into spinal cord injury or into congenital mouse models of hypomyelination [41]--[48].
«Esophageal cancer «cell of origin» identified: In mice, basal progenitor cells give rise to Barrett's esophagus, a precursor to cancer.»
Extra note: see this recent ECCRI paper on circulating progenitor cells in people who have inherited very high cholesterol.
Estradiol's benefits appear related to activation of Endothelial Progenitor Cells which invoke new collateral circulation in areas of injury.
The authors hypothesize that in addition to these functions, epigenetic alterations may also serve as a common trigger through which susceptible and genetically predisposed stem cells become cancer progenitor cells.
Institute director Catherine Verfaille and her team pulled multipotent adult progenitor cells, referred to as MAPCs (and pronounced map - seas), from the bone marrow of mice and rats.
Transplantation of astrocytes generated by exposure of human glial progenitor cells (hGPCs) to BMP (hGDAsBMP) promoted robust behavioral recovery and multi-laminae protection of spinal cord neurons following spinal cord injury (SCI), while transplantation of undifferentiated hGPCs or astrocytes generated by hGPC exposure to CNTF (hGDAsCNTF) failed to provide such benefits.
The team set up a microscope and video camera over several culture dishes, each containing a single neural progenitor cell taken from a mouse embryo 10 days after fertilization.
Special cells called progenitor cells give rise to new taste bud cells that replace old ones.
Celularity is a leader in groundbreaking methods to produce whole organs and organoids from natural and bioprinted scaffolds which can be populated by Celularity's placental stem cells as well as other progenitor cell types.
In the bone marrow, blood stem cells give rise to a large variety of mature blood cells via progenitor cells at various stages of maturation.
Decreased phosphorylation of PDGFR - ß impairs the angiogenic potential of expanded endothelial progenitor cells via the inhibition of PI3K / Akt signaling.
This image shows induced pluripotent stem cell - derived neural progenitor cells after neuronal differentiation.
While progenitor cells live for just months, the researchers found, holoclones last a person's lifetime.
«We discovered that neural progenitor cells show properties that can be associated with the disease and were perfectly suitable for use in large - scale drug screens.
The research demonstrates a method of increasing kidney progenitor cell proliferation in vitro.
We are using live cell imaging, single cell analysis and gene editing to resolve the molecular determinants of human epidermal progenitor cell division outcomes (two progenitors, two differentiating cells or one or each) and the mode of cell division (maintenance mode vs repair mode).
Human Embryonic Stem Cell - Derived Oligodendrocyte Progenitor Cell Transplants Improve Recovery After Cervical Spinal Cord Injury.
Dorian Freudenreich (Brand, TUD)-- «Genetic cell lineage tracing and transcriptome analysis of neuronal progenitor cells during neurogenesis and regeneration of the adult zebrafish telencephalon» (2010)
In collaboration with colleague Aaron Dinner, the research team also formulated a mathematical model that depicts the regulatory network governing progenitor cell development.
While at MIT, his doctoral research elucidated the distinct progenitor cell types that exist within the inner ear and their capacity to form sensory cells and neural cell types.