Sentences with word «nucleic»

I have followed Polanyi's contention that there are organizational principles operative in the universe which formatively influence the specific sequences of nucleic acids in DNA, and with Sheldrake I have postulated the existence of morphogenetic fields which canalize the processes of growth and development in organisms.

The findings, from the Emory / Johns Hopkins / Florida State team that showed this spring that neural progenitor cells are particularly vulnerable to Zika infection, were published in Nucleic Acid Research.

That is, they depend on the host cell for the raw materials and energy necessary for nucleic acid synthesis, protein synthesis, processing and transport, and all other biochemical activities that allow the virus to multiply and spread.

A team led by Beatrice Hahn, professor of medicine at the University of Alabama in Birmingham, has now detected antibodies against the HIV - 1 precursor — along with nucleic acids from the virus itself — in the scat of wild chimps.

The spherical structure of the SNAs is the ideal architecture for delivering nucleic acids into cells for gene regulation, Mirkin said.

Led by Dr. Peter Glazer, chair of therapeutic radiology, Dr. Mark Saltzman, chair of biomedical engineering, and Dr. Marie Egan, professor of pediatrics and of cellular and molecular physiology, the collaborative team used synthetic molecules similar to DNA — called peptide nucleic acids, or PNAs — as well as donor DNA, to edit the genetic defect.

A University of Colorado Cancer Center study recently published in the top - ranked journal Nucleic Acids Research (NAR) describes a database named multiMiR, the most comprehensive database collecting information about microRNAs and their targets.

We have studied a total of 170 samples from chronic fatigue syndrome patients from two UK cohorts and 395 controls for evidence of XMRV infection by looking either for the presence of viral nucleic acids using quantitative PCR (limit of detection < 16 viral copies) or for the presence of serological responses using a virus neutralisation assay.

RNA (ribonucleic acid) a single stranded nucleic acid chain similar to DNA, which serves several important biological roles.

Mediated a patent infringement a case involving patent covering a wide range of Alzheimer's Disease research and technology including nucleic acids for the Swedish mutation and related vectors and cell lines

Scientists are currently investigating ways of using nucleic acids to re-program cells to carry out different functions.

Palazzo painstakingly picked out centrosomes from large and easily manipulated surf clam eggs and detected nucleic acids in the concentrated extract.

Screening the Blood Supply for West Nile Virus RNA by Nucleic Acid Amplification Testing.

The NanoFlares are tiny spherical nucleic acids with gold nanoparticle cores outfitted with single - stranded DNA «flares.»

Over the past decade, healthcare providers have been able to expand screening programs for chlamydia thanks to the development of a highly sensitive method known as nucleic acid amplification testing (NAAT).

They also contain nucleic acids.

Even after initial purification of the sample, liquid biopsies typically contain much more nucleic acid from healthy cells than from tumors.

«Our research supports the development of targeted nucleic acid delivery platforms for therapeutics for autoimmune diseases and cancer,» says Prof. Peer.

DNA repair is a hugely important topic and these three were the first to describe the repair mechanisms,» Thomas Carell, who studies nucleic acid chemistry at Ludwig Maximilians University in Munich, told Science.

Using a combination of old - fashioned clinical observation and modern biochemical analysis, he has shown that a person's appetite and their eating behavior can be linked to specific genes — and that even a tiny defect such as the absence of a single nucleic acid in a sequence of DNA can lead to runaway weight gain.

The new work, like the 199 day finding, looked at nucleic acids and thus does not conclusively prove that the virus in semen can spread disease for 284 days.

Irradiation of the iodouracil chromophore with monochromatic, long - wavelength ultraviolet radiation (325 nanometers) eliminates excitation of other nucleic acid and protein chromophores.

Two projects will be done jointly with the Karolinska Institute in Stockholm: Molecular biologist David Baillie of Simon Fraser University in Burnaby, British Columbia, was awarded $ 6.73 million to study protein function in the soil nematode Caenorhabditis elegans, and microbiologist Sherif Abou Elela of the University of Sherbrooke, Quebec, received $ 3.75 million to test modified nucleic acid technologies for determining gene function.

By injecting short nucleic acids into rats, researchers have blocked an enzyme linked to swelling and tissue damage in the lungs.

IDT's primary business is the production of custom, synthetic nucleic acids for molecular biology applications, including qPCR, next generation sequencing, synthetic biology, and functional genomics.

The TMAdV - specific quantitative real - time PCR was performed on a Stratagene MX3005P real - time PCR system using a 25 µL master mix consisting of 18 µL of water, 2.5 µL of 10X Taq buffer, 1 µL of MgCl2 (50 mM), 0.5 µL of deoxynucleoside triophosphates (dNTPs; 12.5 mM), 0.5 µL of each primer (10 µM), 0.5 µL SYBR green, 0.5 µL of Taq polymerase (Invitrogen, Carlsbad, CA), and 1 µL of extracted nucleic acid.

This special carrier can also be potentially used to co-deliver therapeutic nucleic acids to prevent cancer cells from developing resistance to multiple drugs4.

it is there for very easy to expect that 3.5 - 4 billion years ago there were pools of water full of self replicating nucleic acids.

The field segregates into three major strategies: detecting free nucleic acids, isolating intact circulating tumor cells, and identifying extracellular vesicles from tumors.

The company currently produces nucleic acid, MSG, arginine and histidine at the Jombang plant.

It was a tall order: The first crystals of ribosomes — the cellular factories that translate nucleic acids into proteins — had been obtained in the early 1980s, but there were few labs with either the technical capacity or the desire to determine their structure.

My colleagues and I first undertook to synthesize nucleic acids outside the living cell, with the help of cellular enzymes, in 1954.

«It is the only known nucleic acid platform for treating such ailments and constitutes a new pipeline of therapeutics to address a broad swath of debilitating health conditions.»

The team created mosaic nucleic acids that were half DNA, half RNA.

Magnetic beads have long been used to isolate nucleic acids as well as recombinant proteins.

The technique as proposed would work because nucleic acids like DNA are promiscuous.

They work on microarray - based gene sensors for analyzing nucleic acids quickly and cheaply.

Represented Sugen against The Regents in a patent interference involving the rights to an isolated and purified nucleic acid for Discodin Domain Receptor (DDR) protein.

It also hints at why proteins were eventually preferred by evolution over nucleic acids as catalysts in biology: proteins offer much more ability to «tune» their «jiggling and wiggling» and their response to chemical reactions.

He studies threose nucleic acid, which is not found in nature but can be synthesized in the lab.

Modern molecular technologies (genomics and other omics), through comparing nucleic acid and amino acid sequences across living species, are enabling the identification of genetic components and patterns stingily conserved by evolution, from those in which times of evolutionary branching of the tree of life can be inferred.

For high - throughput screening using fragment analysis, RNA was isolated using a MagnaPure LC system with a MagnaPure LC total nucleic acid isolation kit (Roche) according to instructions from the manufacturer.

Shi, X., Hanson, M.R., and Bentolila S. (2015) Two RNA recognition motif - containing proteins are plant mitochondrial editing factors Nucleic Acids Res 43:3814 - 3825

Rearrangements in the mtDNA will be monitored by long extension - PCR (LX - PCR) and mtDNA point mutations will be analyzed by direct mtDNA sequencing and by Protein Nucleic Acid (PNA)- competitive PCR (PNA - PCR).

Fixation processes significantly damage nucleic acids, and long storage times can produce problematic artifacts.

The only nucleic acid enzymes are ribozymes, which are single - stranded RNA molecules rather than double - stranded DNA.