This includes identifying pancreatic cancer stem cells, the
small number of cells within a tumor that fuel its growth and spread.
Cell lines are therefore indispensable in medical research and a
large number of cell lines exist that originate from many different tumor types.
He observed that normal human cells had a finite lifespan in vitro and could execute only a limited
number of cell divisions.
This method also makes it possible to create a far greater
number of cells for research or regenerative purposes.
To determine what to call a hotspot I simply looked at the X
number of cells with the most tiles / calls.
Beyond its function in the muscles, magnesium is involved in signaling for a huge
number of cell types in the body.
Recent studies highlighted significant differences between these two types of stem cells, although only a limited
number of cell lines of different origins were analyzed.
Previous efforts to screen potential drug combinations only analyzed use of a few drugs against a
limited number of cell lines or lines in which genomic variations were poorly understood.
Human tissues exposed to either drug for one week in a dish had
reduced numbers of cells that give rise to sperm and eggs, called germ cells, the study found.
It would not be as easily achieved, as the total
number of cells needed to build a basic unit would be 43, rather than just four.
Although neural stem cells were dividing at a normal rate, unusually
high numbers of cells died soon after they formed, they found.
It is important to keep in mind that why this process is so successful for embryos and sperm is because of their size and their relative
low number of cells.
To answer these questions, the scientists went in a new direction: They performed infection trials in a large
number of cell cultures at different temperature levels.
The researchers conclude this technique could eventually lead to new ways to prepare
vast numbers of cells for the coordinated manufacture of gene therapies.
Because our bodies freely shed a limited and
select number of cells, many stem cell types must be obtained using a rather invasive procedure.
Despite this, only
small numbers of cells are dividing at any one time, so the treatment is not helpful in all cases.
After an extended
number of cell divisions, random segregation of mitochondria may lead to cells containing a majority of mitochondria from the donor egg.
How do
large numbers of cells, each with only limited local information, collaborate to create something much larger and more complex than themselves?
As CNN and others are reporting, an increasing
number of cell phone gabbers are complaining of an ailment called «cell phone elbow.»
As an
increasing number of cell therapies move into late - phase trials, developers are considering innovative solutions to address scale - up and commercialization challenges.
Clinical Pathology — a veterinary specialist trained to examine, identify, and analyze under the microscope small
number of cells from a needle biopsy.
Diseases of the retina may offer an early test bed for hiPSC - derived cells, in the form of retinal pigmented epithelium, given the relative isolation of the tissue, and the small
number of cells required [14].
The massive
number of cells within the OSVZ of humans «tells us we have to be careful when modeling human brain diseases in mice,» says Kriegstein.
In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow
sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.
Your gut contains trillions of microorganisms — more than 10 times the total
number of cells found in your body.
Amongst the populations that expressed HIGH or MID levels of stem cell surface antigens, coexpression of transcripts for endoderm or mesoderm genes predominated, but in the LOW and NEG populations, there were
significant numbers of cells expressing neural lineage markers, in particular Pax - 6 (Figure 3d).
Fueled by a recent resurgence in public financing and compelling clinical data for indications as diverse as acute macular degeneration and pancreatic cancer, a growing
number of cell therapies are driving toward pivotal clinical studies and commercialization.
The cells in such a brain tumor can display very different characteristics, such as varying cell size or
number of cell nuclei.
The flies missing S6 kinase had the
same number of cells, just 30 % smaller, the team reports in tomorrow's issue of Science.
Another reason why this is good news, as we've said before, is because there is a
massive number of cell phones already in the US in need of homes.
If cortisol is bound to a greater
number of cell receptors, protein breakdown is increased; however, if anabolic hormones such as testosterone and GH occupy a greater number of receptors, protein is enhanced.
One of the team's new biosensors is made from a nanoplasmonic material that is able to accommodate a large
number of cells on a single substrate and to monitor cell proliferation, a fundamental process involving cell growth and division, in real time.
85 Billion
Estimated number of cells in the human brain that are not neurons, according to a 2009 study by Brazilian neuroscientists.
Next the team prioritized 21 drugs for which the yeast druggable targets were involved in the
greatest number of cell - lethal interactions.
The researchers hypothesize that in older people, many of the cell lineages in the blood have reached their
maximum number of cell divisions and died off, leaving the ones that have divided more slowly and, therefore, have accumulated fewer mutations.
Currently, primary hepatocytes are the most common cell model, but their utility is constrained by large variation between donors and a
finite number of cells harvestable from each donor.
Total
numbers of cells positive for any of these markers are reported for uninfected, Type I - infected, and Type III - infected animals at 4 to 5 mpi.
The total
number of cell equivalents tested for detection of FMc was higher in the controls than in the breast cancer cases (mean 8.2 × 104 (95 % CI 7.2 — 9.2 × 104) in controls versus 5.6 × 104 (95 % CI 4.9 — 6.3 × 104) in cases).
He noticed that the fossils, though all the same size, consisted of
different numbers of cells: one, two, four, eight, and so on, up to around 1,000, roughly doubling with each increase.
Certainly we can talk about cancer risk, and we can talk about
rising numbers of cells becoming senescent in response to DNA damage, and researchers can disable DNA repair to observe the shortened life spans that result from such a fundamental breakage in cellular operation, but beyond that it becomes increasingly challenging to quantify effects within the scope of normal degenerative aging.
When one understands the
huge number of cell towers, NEXRAD, and such devices as SBX1 and the use of microwave energy to manipulate entire weather systems, satellites, and others nations doing same, it stands to reason the atmosphere and all life on earth is run through and through with a technology that is slowly killing life.
Many methods already exist for doing this, but they tend to be clumsy and destructive, not allowing researchers to precisely control how and when they insert the DNA or requiring them to burn through large
numbers of cells before they can get it into one.
«The kidney is a very solid organ, which makes it very difficult to bring
enough number of cells upon transplantation,» explains Professor Kenji Osafune, whose lab at the Center for iPS Cell Research and Application (CiRA) at Kyoto University, Japan, is using iPSCs to investigate new treatments for kidney disease.
It was through the analysis of these high - resolution images that the team made the important observation that loss of Alix leads to an increased
number of cells caught in the act of being discharged from the epithelial layer.
Phrases with «number of cells»