Sentences with phrase «optic nerve»

Studies have found beta - amyloid in tissue following traumatic brain injury and as evidence of optic nerve damage in shaken - baby syndrome.

So again, we're taking these exciting advances in optic nerve regeneration and retinal ganglion cell transplantation and asking how do we translate these into the clinic and how do we use biomarkers effectively?

«Until we began to document fossilised brains, nerve cords and optic nerves from the Cambrian, neuroanatomists and palaeontologists did their studies in parallel but didn't really work with each other.

I have been working in the field of glaucoma research, on pathophysiology and diagnostics, for the past 18 years, and have become increasingly interested in the use of advanced imaging techniques for characterization of glaucomatous changes within the retina and optic nerve head.

Importantly, the research team also looked at optic nerves of the central nervous system, which are damaged in glaucoma, and found similar protective effects from the loss of Phr1.

There we're returning to the therapeutic side and finding exciting advances in optic nerve regeneration and retinal ganglion cell transplantation.

As primary risk factor for glaucoma, elevated intraocular pressure (IOP) is often associated with optic nerve damage and loss of vision.

Summary: A major deficit in glaucoma management is that a diagnosis is made or treatment is initiated after there is already evidence of optic nerve cell death or visual field loss.

Harald Junge, Ph.D., CU - Boulder: Determine the effects of trisomy 21 on optic nerve development and function

We seek to determine whether a particular type of imaging, known as «polarization - sensitive» imaging, is capable of reporting on the integrity of sub-microscopic structures within optic nerve fibers at an early stage of damage from glaucoma, preceding their complete degeneration and loss from the eye.

Nerve signals from the eyes travel through optic nerves and split off to both sides of the brain.

Scientists at the Virginia Tech Carilion Research Institute (VTCRI) have revealed the pathology of cells and structures stricken by optic nerve hypoplasia, a leading cause of childhood blindness in developed nations.

Most do not have the more serious optic nerve coloboma or retinal detachment.

«We hope that these cells can eventually lead to new treatments for glaucoma and other forms of optic nerve disease.»

It is progressive and characterized by optic nerve damage.

Oono S, Kurimoto T, Nakazawa T, Miyoshi T, Okamoto N, Kashimoto R, Tagami Y, Ito Y and Mimura O. Pyroglutamic acid promotes survival of retinal gangion cells after optic nerve injury.

Identifying factors that regulate directional growth of regenerating RGC axons to their targets will provide invaluable information on developing future therapies to repair degenerated optic nerve following glaucoma.

A glaucoma suspect is a person who has normal eye pressure but their visual field or optic nerve looks suspicious for glaucoma.

The expert stated that he believed that the woman suffered an injury to the left optic nerve as a result of the nurse's administration of anesthesia.

There's no retinal ganglion cell regeneration or replacement after optic nerve injury.

Retinal ganglion cell loss in a rat ocular hypertension model is sectorial and involves early optic nerve axon loss.

Dr. Otteson studied how retinal ganglion cells turn on and off the genes that regulate the normal patterns of connections during optic nerve development.

In the last several years, researchers have identified gene therapies that can promote optic nerve regeneration.

$ 1 million Woman with recurring optic nerve tumor loses vision in left eye Action: Medical malpractice Attorney: Krysia J. Syska

In March they reported that a liquid made from one such peptide could repair severed optic nerves in hamsters by forming a gel in which stem cells could accumulate and grow.

There are as yet no therapies to repair optic nerve once the damage is done.

We seek in this proposal to determine whether a particular type of imaging is capable of assessing and reporting on the integrity of sub-microscopic structures within optic nerve fibers at an early stage of damage preceding their complete degeneration and loss from the eye.

«Although clinicians have known about optic nerve hypoplasia for some time, the nature of the pathology was not clearly understood,» said Konark Mukherjee, an assistant professor at the Virginia Tech Carilion Research Institute.

Their findings, published online in Investigative Ophthalmology and Visual Science, shed light on the underlying process responsible for optic neuropathy in KPro patients and also suggest a new pathway for preventing optic nerve damage in patients who receive the KPro implant.

The first symptom of a similar problem appeared on my right optic nerve when I was 16 years old.

«There has always been this question of whether optic nerve hypoplasia occurred during development or if the visual system degenerated after the normal course of development.

The subjects also experienced hypoxic effects, as cessations in breathing cause blood oxygen saturation levels to drop, possibly triggering optic nerve damage that can lead to glaucoma.

First based on our completed genetic study we will test if pharmacological inhibition of an identified protein via direct eye injection can promote long distance optic nerve regeneration or whether, based on strong preliminary data, manipulation of another novel gene can induce such regeneration.

Generous support from the Glaucoma Research Foundation allowed us to develop a strategy to comprehensively assess an entire class of biomolecules called lipids for differences that occur during optic nerve regeneration.

Summary: All forms of glaucoma have in common optic nerve degeneration characterized by typical visual field defects, and are usually associated with elevated intraocular pressure, also known as ocular hypertension (OH).

Therefore, to restore visual function in glaucoma patients, it might be necessary to promote injured optic nerves to regenerate and reconnect to their original targets.

Glaucomatous optic nerve injury involves early astrocyte reactivity and late oligodendrocyte loss.

We have two neurobiologists who are studying retinal ganglion cell and optic nerve biology — and that's me and Andy Huberman — and we also have two optical imaging engineers with very different backgrounds — and that's Vivek Srinivasan and Alf Dubra.

Summary: We hypothesize that early estrogen deficiency accelerates optic nerve aging and predisposes this nerve to glaucomatous damage.

This research was prompted by Dr. Townsend's observation of one affected dog (that lost one eye to GRPU) undergoing spontaneous resolution of GRPU (i.e. resolution of pigment deposition on the ALC) in its remaining eye while on daily specific antioxidant supplementation; this supplement has been shown to be neuroprotective in the presence of glaucoma, and thus may help preserve vision (and help preserve optic nerve function) in glaucomatous eyes.

My daughter was born blind, with Septo optic dysplasia (aka optic nerve hypoplasia), cortical migration disorder, hypotonia (low muscle tone), and developmentally delayed.

Subject also suffers apparent optic nerve damage from SXSW - hottie - ogling (one can't look too long at the sun without consequences, after all).

Twenty - five had ophthalmologic changes: 18 with intraocular abnormalities, including macular chorioretinal atrophy, mottled retinal pigment epithelium, and optic nerve pallor; seven with strabismus or nystagmus without intraocular abnormalities.

So no one knew if this resistance to light was due to the missing SCN or the missing optic nerve,» says Blackshaw.

And in transgenic pups whose optic nerves were surgically severed 4 days after birth, retinal axons grew around the gap, finding their way to the proper target areas in the brain.