Sentences with word «suppressor»
A suppressor is a device that reduces or quiets something, like noise or recoil from a gun. Full definition
Other animal models either express oncogenes in a tissue - specific manner or shut down the expression of tumor suppressor genes in the whole tissue.
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These two histones thus have a key role of epigenetic silencing of tumor suppressor genes in breast cancer (and likely other cancers), suggesting that they may represent new therapeutic targets.
«HOXA5 protein acts as tumor suppressor in breast cancer, lab cell study shows.»
Mutations of the VHL tumour suppressor gene in renal carcinoma.
The scientists are planning further study of HOXA5's role in breast cancer, following up on this work and a study published by Sukumar's lab in 2000 that showed a connection between low levels of HOXA5 and the well - known tumor suppressor protein p53.
In the first test using KnIT, the team sought to identify new protein kinases that phosphorylate (or turn on) the protein tumor suppressor p53.
«However, many patients do not respond because myeloid derived suppressor cells (MDSCs), a type of inhibitory cell, are present in the tumour microenvironment.»
According to Eckmann, «The special thing about these processes is that they involve known molecules with very long evolutionary histories, previously receiving attention as suppressors of tumour formation within the context of normal cell division.
He may be no fan of cell phones, but he's a master craftsman, recycling used auto parts to build a sound suppressor for the assassin's rifle.
LA JOLLA, CA — A tightly controlled system of checks and balances ensures that a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc...
Water is one of the best appetite suppressors there is.
Using transplantable tumor models expressing antigen in an inducible manner or spontaneous tumor models expressing nominal antigens, we try to decipher whether the tumor is ignored or leads to deletion, anergy or class switch of the specific immune response or generate suppressor T cells.
Researchers at Penn State College of Medicine, working with Chinese and American colleagues, have discovered a novel way to enhance and restore cancer suppressor activity in B - cell acute lymphoblastic leukemia, resulting in better outcomes in a pre-clinical model of the disease.
On the other hand, aberrant expression of miR - 7 was observed in glioblastomas, and it has been characterized as a putative tumor suppressor by targeting EGFR and AKT (23, 24).
Conjugated linoleic acid (CLA) up - regulates the estrogen - regulated cancer suppressor gene, protein tyrosine phosphatase gamma (PTPgama), in human breast cells.
This suggests that one or more of the social competence variables acts as suppressor on gender and that with social competence level kept constant differences between boys and girls in trajectory group membership do occur.
These data confirm that LARP7 protein levels are also reduced during breast cancer progression, and thus suggest that LARP7 may play a potential tumor suppressor role in breast cancer.
The Flash Suppressor now also works as a recoil compensator, reducing the Vertical Recoil by a weapon specific value.
With help from postdoctoral fellow Peter de Keizer, former graduate students Lilli Zhou and Adam Freund, former fellow Francis Rodier, consultant Pierre Desprez and fellows in the Hughes and Kapahi laboratories Melissa Sarantos and Su Liu, Remi identified cortisol and corticosterone as potent suppressors of the deleterious secretions of senescent cells.
Some examples of crutch perks would include Stopping Power from COD 4 / Modern Warfare Remastered, Stalker and SitRep Pro from Modern Warfare 3, Toughness from Black Ops II, and Blast Suppressor from Advanced Warfare.
112.3 pounds of kinetic energy thrust arrows at amazing speeds, all made suppressors to make the Blackout as stealthy and silent as possible.
The studios use computer - controlled scratch suppressors when preparing old music for release on CDs.
Such suppressor genes serve as a kind of molecular braking mechanism to control cancer's runaway cell division.
Differential expression of KAI1 metastasis suppressor protein in renal cell tumor histological subtypes.
By analogy to tumor supressor genes, which restrain cell proliferation, we propose that these inhibitory constraints on memory storage, which restrain synapse growth, be termed memory suppressor genes.
Therefore, Numb controls both an oncogenic pathway (the Numb: Notch axis) and a tumour suppressor pathway (the Numb: p53 axis).
On the one hand, autophagy functions as a tumor suppressor mechanism by preventing the accumulation of damaged organelles and aggregated proteins.
Fluoride is effective as a thyroid suppressor at doses of 0.9 - 4.2 mg per day for hyperthyroidism.
It is effective as a thyroid suppressor at doses of 0.9 - 4.2 mg per day for hyperthyroidism.
PI3K - AKT signaling has been reported to promote the activation of the oncoprotein HDM2 and to downregulate the p53 tumor suppressor [28], and therefore AKT is defined as a survival factor.
It has deadening string suppressors as well to help you avoid startling prey.
A UNC Lineberger Comprehensive Cancer Center discovery of just how a certain tumor suppressor molecule works to prevent tumor growth could lead to a personalized treatment approach for colon cancer.
Her lab did this through a large genetic suppressor screen using the fruit fly, Drosophila melanogaster.
A nucleus - encoded suppressor defines a new factor which can promote petD mRNA stability in the chloroplast of Chlamydomonas reinhardtii
Our group aims at characterizing shared cellular mechanisms involved in muscular dystrophies and at identifying broadly efficient genetic and pharmacologic suppressors of muscle degeneration.
Schaefer, A.; Sampath, S. C.; Intrator, A.; Min, A.; Gertler, T. S.; Surmeier, D. J.; Tarakhovsky, A.; Greengard, P. Control of Cognition and Adaptive Behavior by the GLP / G9a Epigenetic Suppressor Complex.
They do this by activating growth - promoting oncogenes (cancer genes), inactivating suppressor genes and altering the genes that regulate normal, programmed cell death (apoptosis).
This gun, like many others, can have attachments like scopes and sound suppressors attached to it to increase state and usage.
Bohemia Interactive have overhauled many features to do with how shooting feels, tinkering with weapon handling, gun sounds, and even adding suppressor and bipod attachments.
Either ignition noise - sparks etc or a whine - from the alternator can be cured by purchasing and fitting suppressors designed for the job.
In the predictions of Reliable Change of parent - reported internalizing and externalizing child symptoms, non-anxiety comorbidity could be classified as a classical suppressor variable.
«Tumor - suppressor connects with histone protein to hinder gene expression.»