Sentences with phrase «population of cells»

Over time, specific populations of cells in the brain become dysfunctional or die.

Scientists can use the technique to develop populations of cells with abnormalities that lead to disease.

A single tumor is composed of many different populations of cells.

Although their function is not completely understood, a special population of cells covering the blood vessels on the brain's surface is thought to contribute to the organ's protection.

She works to isolate populations of these cells, discover how the body regulates them, and understand how they can be used to treat disease.

Once they had pure populations of cells, they compared their patterns of gene expression, as well as changes in the structure of the DNA.

In the last few years, a bulk of data pointing to a small population of cells in tumors that maintain tumor growth, are particularly resistant to chemotherapy, are responsible for relapses, and develop metastases.

With a large population of cells from one parent or from an embryo created from both parents» gametes, vectors could be created to convey the desired gene sequence.

A new paper published online in the journal Cancer Research, «CCR5 governs DNA damage and breast cancer stem cell expansion,» describes the research, which shows that the co-receptor for HIV is found on a small population of cells within human breast cancers.

In summary, human ES cell cultures contain a heterogeneous population of cells with continuously variable expression of pluripotency genes and co-expression of lineage specific genes.

To further address what the co-expression of these markers represented, we purified populations of cells from ES cell culture based on the expression of the Venus transgene and SSEA - 1 by flow cytometry.

Your fatty tissue is also home to a mixed population of cells which are able to secrete vital growth factors.

This gave a mixed population of cells with 20 % expressing CD34, a hematopoietic stem cell marker, with some co-expression of endothelial cell markers (CD31, Flk1, and VE - cadherin).

In a sort of molecular «Where's Waldo,» scientists are often left with no choice but to measure a disease's effects on populations of cells, rather than a single cell.

The center will develop new single - cell approaches that overcome limitations inherent in traditional techniques — which analyze bulk populations of cells, thereby obscuring individual cell behavior.

Scientists say the new approach to growing so - called induced pluripotent stem (iPS) cells is an important step toward creating safe and reliable populations of cells for research and therapy.

«What our findings show is that the problems with iPS cells don't just involve one or two or a few abnormal iPS cells escaping into the body and forming tumors, but that the whole population of cells is screwed up,» Lanza says.

The KU researcher said that new evidence suggests that cancer originates and progresses by a small population of cells known as cancer stem cells.

New techniques have made it possible to study the arrangement and interconnections of entire populations of cells

«What we have to recognize... is that if cancer is a mitochondrial metabolic disease and you get cancer because of mitochondrial failure in certain populations of cells and certain tissues, if you prevent your mitochondria from entering into this dysfunctional state... [then] the probability of getting cancer is going to be significantly reduced.

«The successful retrieval of memories in AD mice by increasing the number of spines for normal memory processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of neurons and their circuits for future therapies.

Molecular biologists have long considered themselves reductionists, but with a frustrating limitation: While they can sequence DNA and RNA with astonishing speed and accuracy, the resulting data represent populations of cells, not individual genomes.

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

Reporting their laboratory findings in the journal Aging, the team observed that addition of DPI to a mixed population of cells eliminated the tumour initiating cancer stem cells.

The tumor microenvironment is comprised of heterogeneous populations of cells including cancer, immune and tumor associated stromal cells.

Since synchronized oscillations between populations of cells distinguished between visual stimuli, it's theoretically possible to determine the correct answers for the matching tasks the monkeys performed simply by reading their brain waves.

In the clearest possible case, the ANT - OAR cell would differ from a zygote on all of the parameters noted above: The ANT - OAR cell would have a pattern of gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of cells rather than multiple cell types; it would undergo simple cleavage divisions and not produce any multicellular structures.

Instead, the team used functional magnetic resonance imaging (fMRI) to detect populations of cells that seemed to fire as the volunteers played a virtual reality game in which they had to replace an object in the location where they originally found it.

They then examined the responses of a specific population of cells, specifically CRH neurons which control the brain's response to stress, in each mouse, which revealed that networks in the brains of both the stressed mouse and naïve partner were altered in the same way.

Within a single tumor exists such an astonishingly varied population of cells, each with its own combination of normal and abnormal genes, that at least some cells nearly always have a way to survive any particular attack.

Researchers in this study used budding yeast, creating populations of cells with more than 10 million different randomised genomes, to investigate how genetic diversity affected resistance.

At one level, optogenetics is nothing more than using light to control a targeted population of cells.

«What David's group can do is grow populations of cells in a very miniaturized state in ways that they can reach out and talk to each other through tiny channels, but yet they stay distinct,» den Boon says.

«Computer - based classification of cells based on large population of cell images opens up new perspectives.

In order to eradicate those HIV reservoirs, researchers must find a way to eliminate persistent populations of cells with integrated HIV proviruses.

The study, which appears August 3 in the peer - reviewed journal Nature Communications, showed that pairing the chemotherapy with an experimental drug eliminates the deadly population of cells believed to be responsible for repopulating the tumor.

«The surprising result is that even though only a very localized population of cells is used in the brain - computer interface, the brain recruits many other areas that aren't directly involved to get the job done.»

Located near the center of the brain, the nucleus accumbens is connected, by intermingled populations of cells, to many other brain structures having roles in pleasure seeking and drug addiction.

Researchers at Dana - Farber Cancer Institute this year announced that a previously unrecognized population of cells in the lymph nodes signals the immune system to tolerate conditions that would normally prompt an attack.

That is, they contained multiple populations of cells, including the so - called JARID1B cells, which their research suggested was responsible for allowing tumors to survive drug therapy.

«We have identified two new populations of cells in the brain that potently regulate appetite,» says Alexander Nectow, first author of the paper, published in Cell on July 27.

This is useful when only certain populations of cells need to be «fixed.»

Sheer mass is a major issue — it's very difficult to nourish a 3 - D population of cells in the lab on the scale of a liver.

If chemotherapy piles on an additional lingering population of these cells, secreting signals that disrupt metabolism and degrade tissue function, then do we call that accelerated aging?