Sentences with word «apoptosis»

This is achieved via an IL -22-mediated increase in proliferation and inhibition of apoptosis of epithelial cells and stem cells [22 — 24].

Many natural medicines, including dandelion and other ones present in the EndAllDisease collection of Cancer Cures, can be used to assist in inducing apoptosis in diseased, or cancerous cells.

Thus, VPA did not reduce GVHD by inducing apoptosis of CD4 + effector T cells.

Researchers at the Beihang University School of Biological Science and Medical Engineering, led by Dr. Yubo Fan, have discovered that Biphasic Electrical stimulation (BES), a non-chemical procedure, may be used as a strategy for preventing cell apoptosis in stem cell - based transplantation therapy.

IG20 (MADD splice variant - 5), a proapoptotic protein, interacts with DR4 / DR5 and enhances TRAIL - induced apoptosis by increasing recruitment of FADD and caspase - 8 to the DISC.

[10] Methyl jasmonate, a plant stress hormone produced by many plants including rosemary, olive, and ginger, inhibits HK, triggering apoptosis in cancer cells.

In a xenograft KMT2D - mutated T - lymphoma model, dual treatment with chidamide and decitabine significantly retarded tumor growth and induced cell apoptosis through modulation of the KMT2D / H3K4me axis.

Giving the mice antibiotics helped gemcitabine kill tumor cells, increasing the number of tumor cells going through a type of cell death called apoptosis from about 15 percent to 60 percent or more.

The scientists discovered that dinaciclib, by interfering with UPR activation, caused multiple myeloma and myeloid leukemia cells to initiate a form of cell suicide known as apoptosis when exposed to agents that induced ER stress.

As reported previously, inhibition of PI3K resulted in increased apoptosis of ALCL cells (5).

Different complex carbohydrates (serving the function of pre-biotics) feed different strains of intestinal flora and promote good intestinal health, providing short chain fatty acids for the cells of intestinal lining as a source of energy and also create a pH favoring good intestinal health — this all reducing the risk of cancer, also by controlling the proliferation and promoting apoptosis of the intestinal lining tissue.

Several potential mechanisms have been suggested: autophagy promotes metabolite turnover and absorption in tumor cells to meet their high demand of metabolism and growth; autophagy inhibits apoptosis caused by mitochondrial malfunctions and ROS production; or autophagy increases drug resistance [21].

The figure shows a confocal microscopy image of a mammalian cell undergoing apoptosis with the mitochondria stained in magenta and the protein Bax in green.

The benzamidazole mebendazole significantly inhibited growth of adrenocortical carcinoma cells, both in vitro and in vivo, the effects being due to induction of apoptosis [19].

However, Mori confirmed in an e-mail that the problematic publication is «Downregulation of citrin, a mitochondrial AGC, is associated with apoptosis of hepatocytes,» which appeared in the 28 December 2007 issue of Biochemical and Biophysical Research Communications.

In the study, the biomedical engineers killed the cancerous tumor cells within days, by injecting liposomes armed with TRAIL (Tumor necrosis factor Related Apoptosis - Inducing Ligand) that attach to «natural killer» cells — a type of white blood cell — residing in the lymph nodes.

«What was especially surprising and exciting was that a non-chemical procedure can prevent apoptosis in stem cells therapy for spinal cord injury patients,» Fan said.

Xiang, Y., Wang, Z., Murakami, J., Plummer, S., Klein, E.A., Carpten, J., Trent, J., Isaacs W., Casey, G., and Silverman, R. H. Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2», 5» - oligoadenylates.

However, the 37 - 40 kDa cleaved fragment of beta actin can be generated during apoptosis process.

Altieri and his colleagues have used biochemical and genetic approaches to study the role of survivin in apoptosis inhibition, and how this process enables aberrant cell viability in tumors, as well as resistance to therapy.

Angiopoietin - Like 4 Confers Resistance to Hypoxia / Serum Deprivation - Induced Apoptosis through PI3K / Akt and ERK1 / 2 Signaling Pathways in Mesenchymal Stem Cells

Gradual increase of p53 levels activates apoptosis promoting protein Bak on the surface of the mitochondria making these cells vulnerable to death.

3 Interestingly, lithium increases BCL2, which blocks apoptosis (cell death) and is decreased during fasting.

ATR - Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine.

TRAIL - enhanced apoptosis as measured by cleavage of caspase - 3 (Fig. 4I), and knockdown of ABL kinases increased the sensitivity of 1833 breast cancer cells to the proapoptotic effects of TRAIL (Fig. 4, G to I).

The Altieri laboratory is interested in how tumor cells evade apoptosis — also known as programmed cell death — which is the process that normally causes dysfunctional cells to self - destruct.

In upcoming investigations, the scientists want to verify their findings on the development of liver cancer and search for active substances that inhibit apoptosis while simultaneously causing the mildest possible side effects.

Manduca hemocytes also undergo apoptosis when exposed to recombinant Mcf1 [19].

To study the underlying apoptotic mechanisms, expression of apoptosis regulators was assessed after treatment with rapamycin or specific mTOR siRNA.

Blocking the mechanisms involved in other methods of cell death including apoptosis and phagocytosis did not disrupt the process, confirming that entosis operates in a different way.

In our study, CD8 − T cells from CD4 KO rejector mice failed to display CTL or DTH activity, yet they were capable of inducing donor - specific apoptosis of corneal endothelial cells.

PromoKine offers a wide range of well proven products for cell biology research such as kits and reagents for cell analysis, apoptosis research, cell transfection, fluorescent labeling, gene cloning & expression, mycoplasma detection and elimination as well as numerous antibodies, ELISAs, cytokines and growth factors.

Not only do controllers have more CD8 T cells, each cell produces greater quantities of perforin and granzymes, which stimulate apoptosis, or cell death.

She earned a Ph.D. from the University of Southern California in which she characterized the mechanisms of sex hormone - induced neuroprotection against apoptosis associated with Alzheimer's disease (AD).

Just because the recent study focused on ALM doesn't mean avocotin B converts only ALM cancer cells into apoptosis.