Sentences with phrase «tumor types»
The phrase "tumor types" refers to different categories or kinds of tumors. Tumors are abnormal growths in the body and they can occur in various areas. Each tumor type has its own distinct characteristics and can affect different parts of the body. Full definition
Single - cell DNA solid tumor profiling enables high resolution of the genomic diversity in a variety of tumor types.
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They are being tested in dozens of other tumor types as well, so the competition will only get hotter.
Cell lines are therefore indispensable in medical research and a large number of cell lines exist that originate from many different tumor types.
A common feature of cancer across many tumor types is that patients fall back into the state of illness after apparent recovery.
Another challenge is acquiring high - quality biological samples needed for genomic studies, particularly for tumor types that are uncommon or rare, or those not treated primarily by surgery.
By exploiting these differences, scientists have developed therapies that target specific tumor types, and these targeted therapies have proven useful against most breast cancers.
She is particularly interested in the identification of cancer driver mutations, genes and pathways across tumor types and in the study of their targeted opportunities.
Also, multiple tumor types might be present, and you can make the wrong interpretation with just this test.
The biological behavior, prognosis, and treatment of these tumors depends on tumor type, primary site (location), and extent of disease (stage).
There are many good reasons for this, but with low - cost whole genome sequencing I think that we can explore the whole genomes of rare tumor types as well.
Knowing more about tumor types and their possible locations can help you monitor your dog and catch cancer early, which may help treat the disease before it gets out of control.
Manage and enroll patients using established molecular profiling and large referral bases to include common and uncommon tumor types.
To distinguish tumor type and reach an accurate diagnosis, surgical invasion will be needed to obtain the appropriate tissue samples.
These signaling molecules may also play a role in tumor development in other organs, and are being evaluated in melanoma and other tumor types.
Ultimately, this knowledge may shift the paradigm of treating specific cancers of origin such as breast, lung and colon to treating unique mutations shared by many different tumor types.
Our team designs and delivers radiation treatments optimized to each patient's specific tumor type, size, stage and location.
Once you have that diagnosis, here are some of the things from my experience with a variety of tumor types.
The transcription machinery the compound shuts down is common among all cancer cell types, so the researchers believe it has therapeutic potential across many tumor types.
Our research shows that Tumor Treating Fields have an antimitotic effect in more than 18 solid tumor types in culture and in eight in vivo tumor models.
Johnson is the principal investigator of an international patient registry of individuals with the cancer syndrome Neurofibromatosis Type 1 (NF1) who incur a strongly increased risk for various tumor types, including pediatric brain tumors.
We will also perform needle aspirates, which is a form of biopsy where a needle is inserted into the tumor to collect cells for use in determining tumor type.
The study evaluated the efficacy and safety of cabozantinib compared to placebo in 9 different solid tumor types including breast, lung, ovarian, and prostate.
PKC is also a well - established anti-apoptotic factor expressed in several tumor types.9
Global cancer genomics research also helps us understand geographical hotspots for certain tumor types.
Treated tumor types include hepatocellular carcinoma, cholangiocarcinoma, neuroendocrine tumor, colorectal cancer, breast cancer, melanoma, and soft tissue sarcoma.
To develop the methodology, the group analyzed the molecular profiles of human embryonic stem cells and compared them with data for 12,000 samples of 33 different tumor types held by The Cancer Genome Atlas (TCGA), a US public database.
In a study published in Nature, researchers lead by Cédric Blanpain, MD / PhD, WELBIO investigator and Professor at the Université libre de Bruxelles, Belgium, in collaboration with Pr Wayne Phillips, Australia and Pr Christos Sotiriou, Bordet Institute, Belgium, uncovered the cellular origin of PIK3CA - induced breast tumors and demonstrated that the cancer cell of origin controls tumor heterogeneity and is associated with different breast tumors types and clinical prognosis.
In the case of several major tumor types, the collagen matrix plays a critical role, Eliceiri says.
Comprehensive and compassionate treatment of breast cancer patients with an interest in aggressive tumor types like IBC
The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.
Researchers studying the brain tumor type glioma often use a cell line called U87MG that was established at Uppsala University almost fifty years ago.
«The additional information we can now derive from tumor biomarkers such as E-cadherin, nm23 and microvessel counts should begin to allow us to tailor therapy according to individual tumor types,» added Samuel Hellman, MD, A.N. Pritzker Distinguished Service Professor of radiation and cellular oncology at the University of Chicago and co-author of the paper.
Previous studies characterizing MELK expression in triple negative breast cancer and other aggressive tumor types somewhat diminish the novelty of this work.
In some cases, survival time after surgery have be tripled in patients treated aggressively with surgery [those with large resections lived 3 years and those treated with only tumor removal in the same tumor type lived 1 year]
Definitive diagnosis of tumor type relies upon microscopic examination of tissue.
In recent years, my laboratory has discovered driver mutations, which confer a selective growth advantage and thus promote cancer development, for certain rare tumor types.
In other words, different pediatric tumor types seem to arise from different mutated genes and pathways.
For example, TCGA, with genomic data on 33 tumor types taken from samples from 11,000 patients, is finishing 2018 by publishing a series of papers and holding a symposium.
«We now hope to move on to investigate how these bacteria contribute to the development of the characteristic stomach tumor types that are associated with each of these conditions.»
Andreas Plückthun is optimistic: «Now that we have identified the Achilles heel of HER2 - positive cancer cells, new opportunities are opening up for treating invasive tumor types like breast cancer more effectively in the future.»
The researchers next will turn to analyzing the presence of myoferlin in samples from numerous human tumor types available in an Ohio State tissue bank, which will allow them to compare protein levels in tumors to clinical outcomes for the patients who provided the samples.
«This aspect of the research is one of the most intriguing findings to come out of the TCGA program, which has been looking at more than 30 tumor types over the past decade.»
The company is assembling preclinical data to determine whether LAMP nucleic acid constructs can amplify and activate the immune response in highly immunogenic tumor types.