To try to determine how those changes influenced the gene's function, that group put the human
version of the gene in mice.
Then they slipped a
human version of each gene into yeast cells whose own copy of the gene had been turned down, turned off, or removed.
Another possibility was that all of the diversity in the bacterial genes is «neutral» — no
particular version of a gene makes an organism more or less fit for its environment.
Although these sorts of studies are tricky to do, they suggest that people with
certain versions of genes appear to be more likely to bounce back after adversity.
However, just because you have a
short version of the gene doesn't mean you won't get the disease — it just decreases your risk.
Now a study shows that the protein built by
healthy versions of the gene binds directly to DNA, suggesting that the protein might repair DNA damage.
Patients who had changed
versions of this gene showed early promise, often attending college, but then experienced cognitive decline consistent with a degenerative disease.
For example, a researcher could modify a rat genome to contain a
broken version of a gene necessary for female fertility, and introduce some of these rats to an island.
By 12 months of age, infants with this gene variant whose needs were consistently attended to responded to stress just as effectively as did the babies with
other versions of the gene.
Additional research is also needed to determine how the
C version of the gene affects the protein's function.
Specifically, how does evolution shape the same gene to be adapted to tropical habitats in one lineage, while adapting an
alternate version of that gene to cold habitats?
The researchers have not attempted to add any new genes or change traits, only to correct a disease -
causing version of a gene.
Different
versions of genes at each location can lead to higher or lower protein concentration in soybean.
Their DNA contains two copies of a gene that most dogs only have one of — the second copy is an
old version of a gene borrowed from wolves.
Some studies have found that people who are resilient to trauma are more likely to have
certain versions of genes that make proteins involved in the stress response.
«In two studies of breast - fed infants involving more than 3,000 children in Britain and New Zealand, breastfeeding was found to raise intelligence an average of nearly 7 IQ points if the children had a particular
version of a gene called FADS2.
North and her co-workers found that the region surrounding the
mutant version of the gene showed less variability than did other parts of the genome, a sign of positive natural selection.
The at - risk haplotypes, or
versions of the gene linked to obesity, were found in more than one in four individuals with high BMI, and were three times more common in these individuals than in controls.
Another discovery in D. melanogaster, said Shah, is that neurons in the fly's brain, expressing male - specific
versions of the gene known as fruitless, «seem to connect up with these Gr32 - sensing neurons on the foreleg.
Through its population genetics research in Iceland, deCODE identified common
versions of the gene encoding EP3 (the PTGER3 gene) that confer increase in risk of PAOD.
Perhaps «wild - type» (Red Junglefowl)
versions of this gene also help hybrids build brains that can respond to dangers of the wild, such as nosy biologists» traps.
The study illustrates the genetic foundation of evolution, including how genes can flow from one species to another, and how different
versions of a gene within a species can contribute to the formation of entirely new species, the researchers report in the journal Nature.
The study team injected patients with a vector, a genetically engineered adeno - associated virus, which carried a
normal version of a gene called RPE65 that is mutated in one form of LCA.
Faeders and satellites both harbour mutations near a gene that breaks down testosterone, and Andersson speculates that an
overactive version of this gene explains why faeders and satellites are not aggressively territorial.
To ensure the introduced protein didn't interact with other parts of the neuron, the team used the mouse
version of the gene rather than the nematode's usual invertebrate version.
The gene affects credit - card debt the way other genes have been found to play a role in breast cancer: a particular
version of the gene increases risk, but many other genetic and environmental factors are important, too.