Sentences with phrase «change in cells»

Machine learning combined with molecular paints allows rapid screening of changes in cell shape and function.

By using computerized image processing to assess multiple clues at once, the technique can pick up subtle changes in cell function in response to drugs, toxins, and other factors.

The current research findings build upon recent discoveries including novel identification of key genetic changes in cells of the immune system.

Researchers are looking into methods that might discern changes in cell structure that result from freezing the blood.

There is no significant change in cell size or structure and the cells typically remain normal.

These substances enter the bloodstream and jump - start changes in cells far from the muscles themselves.

Those analyses have long relied on qualitative changes in cell shape to track physiological shifts.

Such mutations can be caused by the sun, smoke, radiation, or other random changes in the cell.

It takes only a tiny amount to cause big changes in cells or even your whole body.

Changes in the cell structures of some foods can take place during the freezing process.

Consisting of long, sugar - decorated molecules called glycoproteins, the coating causes physical changes in the cell membrane that make the cell better able to thrive ¬ — leading to a more lethal cancer.

In addition to the above mood and anxiety roller coaster, sugar causes changes in our cell membranes, in our arteries, our immune systems, our hormones, and our gut, as I discuss here.

Positive selection of developing thymocytes is associated with changes in cell function, at least in part caused by alterations in expression of cell surface proteins.

Most of the proposed mechanisms of actions in these studies involve changes in cell signaling and decreased production of pro-inflammatory cytokines.

They will focus on the interrelation between drug - induced changes in the cell structure and protein transport as well as the disease - related deregulation of this process.

The results show that enhancer transcription causes long - term epigenetic changes in cells.

Researchers showed that BEZ235 reversed infection - induced metabolic changes in the cell and reduced production of new flu virus.

Aberrant regulation of the epigenetic information results in changes in cell fate decisions, thereby affecting development and tissue homeostasis, and ultimately leading to disease, such as cancer.

Consisting of long, sugar - decorated molecules called glycoproteins, the coating causes physical changes in the cell membrane that make the cell better able to thrive --- leading to a more lethal cancer.

However, the basic mechanism of activation is the same for all receptors: a ligand — for example a hormone, growth factor, cytokine, or nutrient — binds to the receptor and triggers changes in the cell's metabolism and activity.

Those data were then combined with information about functional changes in cell behavior to develop a nanomechanical profile, or phenotype, for specific cellular states.

Consequently, despite the extensive and highly successful efforts of many researchers to develop infection models in Drosophila, the outcomes of infection are often measured by end - points such as insect death (survival of a cohort of insects over time) or changes in cell morphology at fixed periods throughout infection (often monitored by staining different elements of the cytoskeleton).

Up to 70 per cent of human cancers, including many leukemias and lymphomas, have unusually high levels of MYC, which causes cancerous changes in cells by forcing them into abnormally rapid growth.

The alterations leading to tumour development are due to multiple changes in cell physiology and specifically in the cell genome.

Cancer is a complex disease involving numerous changes in cell physiology including the metabolic process on how it may be fed.

The researchers found that Myc activates cancer - like changes in cell metabolism, causing a sudden fall in ATP concentration inside the cells.

These studies claim that those chemicals may then interact with DNA and lead to cancerous changes in cells, or interfere with the action of the female hormone estrogen, which is known to influence the growth of breast cancer cells.

For example, next - generation sequencing can be used to read the complete genetic information of a biological sample, DNA chips directly measure the activity of thousands of genes simultaneously, mass spectrometry characterizes proteins expressed in a tissue, high - resolution imaging tracks changes in cell cultures, and high - throughput screening characterizes the biological activity of a large number of molecules.

Methods: The team profiled lipids using analytical chemistry techniques and monitored changes in cell shape using capabilities in the Quiet Wing at EMSL, a Department of Energy national scientific user facility located at PNNL.

By contrast, no significant changes in cell proliferation were seen following transient transfection with control 4E - BP1 siRNA.

You vary («calibrate») conductivity and potential change per unit mass change in each cell until your model can reproduce the observed values over a given historical period.

Their goal is to enhance the current visual data that these scientists are working with so that it's easier to identify changes in cells over time - information that is key to studying the abnormal cell proliferation that causes cancer and also to using stem cells in regenerative medicine.

«The genetic changes in these cells lead to protein changes on the cells» surface which make them an excellent target for a person's immune system to react to,» says Gan.

Those tests will answer basic questions about changes in cells and genes; they are not the elaborate, years - long studies exposing lab animals or examining humans that can answer most important health questions.

Certain low - risk strains — there are, in fact, more than 100 types of HPV in all — can cause genital warts or benign or low - grade changes in the cells of the uterine cervix.

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

Somatic gene therapy can be broadly split in to two categories: ex vivo, which means exterior (where cells are modified outside the body and then transplanted back in again) and in vivo, which means interior (where genes are changed in cells still in the body).

Further investigation revealed that loss of surrounding cells causes multiple changes in cell communication, which impairs bone cells» ability to multiply and increase in size.

Sure enough, some of the chemicals sparked a «smell response» in the neurons, as reflected by electrical changes in the cells, the researchers report online today in Nature.

«Our research demonstrated and supports earlier research from elsewhere that changes in cells occur before you can see them.

The researchers teamed up with members of the Rockefeller University proteomics facility to see how protein expression changes in cells with elevated levels of these two tRNAs.

In this study, we show that manipulation of dietary carotenoid supply invokes parallel changes in cell - mediated immune function and sexual attractiveness in male zebra finches (Taeniopygia guttata).

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

Kinney is leading a team researching the role of several risk factors and subtle changes in cell function associated with Alzheimer's disease, including interactions between diabetes and inflammation in the brain in the onset and progression of Alzheimer's disease.

Although infiltration of NKT cells were not observed, the investigators speculate that changes in this cell population could be transient.

They showed that Sestrin1 exerts its anti-tumor effects by blocking the activity of a protein complex called mTORC1, which is well known for controlling protein synthesis as well as acting as a sensor for nutrient or energy changes in the cell.

The immediate application of the research, Sinha explains, is in helping scientists pinpoint important changes in cell behavior.