Sentences with word «haplotype»

The graph shows the number of haplotypes found in a survey of each breed, separated into Class I and Class II DLA.

Another important factor in reading and writing disabilities, READ1, a polymorphic compound with a short tandem repeat within intron 2 of risk gene DCDC2 may have a non-additive genetic interaction with KIAHap, a risk haplotype in risk gene KIAA0319 may be a transcriptional regulator of ETV and so also a transcriptional regulator of KIAA0319.

The HapMap, a shorthand for haplotype map, gauges diversity in the maize genome by comparing 27 distinct genetic lines of the plant with the reference version.

MEIS1 intronic risk haplotype associated with restless legs syndrome affects its mRNA and protein expression levels.

Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting.

This indicated that the over-representation of certain haplotypes occurred at the onset of breed creation as a result of small founder numbers, and / or that it was associated with artificial genetic bottlenecks that were subsequently masked by a return to random selection.

Intriguingly, the new genetic resistance locus lies within a region of the genome where humans and chimpanzees have been known to share particular combinations of DNA variants, known as haplotypes.

We also performed the first example of cross validation using complementary CC resources to verify the effect of sperm curvilinear velocity from the PWK / PhJ haplotype on chromosome 2 in an independent population across multiple generations.

By identifying haplotypes from single - molecule reads, the authors were able to construct phylogenetic trees of the leukemic cells in a single patient, something that could only be done on the 454 platform.

The genetic markers on high - density SNP arrays are carefully chosen to capture (or «tag») most common haplotypes in human populations.

We determine the Paternal Haplotype by looking at a dog's Y - chromsome — but not all dogs have Y - chromosomes!

After months of passing the hat among countries and private companies, the U.S. National Institutes of Health (NIH) announced today that it has garnered the $ 100 million the 3 - year effort to construct a so - called haplotype map is likely to cost.

When Dr. Foley approached me to see if I was interested in the program coordinator position, I was working as postgraduate researcher on a project to identify the origins of the domestic dog through Y chromosome haplotype analysis.

The failure of all mtDNA haplotype lineages within P. blainvillii to coalesce between T1 and the present results in an opportunity for deep coalescence between P. blainvillii and P. cerroense.

The short size of the locus was ideal for 454 sequencing, and because single - molecule reads are generated, the authors were able to identify haplotypes of somatic hypermutations carried by individual leukemic cells.

«For instance, the benefits of the new UK10K haplotype reference panel are already being realised in analyses of international consortia as well as the 0.5 M people UK BioBank study.»

To study natural selection, the team combed the International Haplotype Map for long stretches of DNA flanked by a single nucleotide polymorphism (SNP, or «snip»)-- that is, an altered base, or «letter,» in the genetic alphabet.

So when we find the same haplotypes [blocks of DNA sequence around the gene] in Quebec, we are proving the common European root.

mtDNA sequences from the 166 individuals were aligned with published sequences from 17 additional individuals, resolving 52 unique haplotypes from a consensus length of 410 bp.

On detecting incomplete soft or hard selective sweeps using haplotype structure Ferrer - Admetlla, A., M. Liang, T. Korneliussen, and R. Nielsen.

On detecting incomplete soft or hard selective sweeps using haplotype structure.

Although none of the CEU contributors appeared to be direct descendents of the two men, based on haplotype analysis, I was able to make predictions for the surnames of the CEU participants by the same process.

The inter-breed differences in DLA haplotypes associated with susceptibility to canine hypoadrenocorticism could represent divergent aetiologies.

We assessed shared ancestry and admixture, relationships between haplotype heterozygosity and geography, and population differences in copy number variation throughout the human genome in the 1,043 individuals.

While the new Y haplotype does increase the diversity, and thus the TMRCA, the TMRCA calculation is extremely sensitive to the mutation rate used.

Chromosomal regions harboring candidate genes were evaluated for SNP haplotypes with frequencies of 1.0 in the CMS cases and between 0.14 and 0.50 in the controls.

Moreover by providing long - range information, it could also solve haplotype phasing.

There are at least two potential causes for this non-random distribution: past population structure, and a large demographic bottleneck that resulted in the reshuffling of haplotype frequencies.

On further culture or after subcloning this ES cell line at various times (passages), this particular mtDNA haplotype showed essentially random drift, with cells carrying anything from 0 to 100 %.

In the 46 bone samples that yielded results in the new study, the team's tests uncovered 14 different haplotypes, or particular sets of genetic variation, 10 of which had never been seen in previous studies.

Analyses that examine haplotype blocks would begin to elucidate the true causal genetic variants to behavioral phenotypes.

The unique barcoding system of Gemcode allows genetic variants detected in short sequence reads to be ordered into haplotypes experimentally.

Confirmation that a specific haplotype of the dopamine transporter gene is associated with combined - type ADHD

The methodology and data gained from this study will identify the level of diversity of DLA alleles in different breeds and enhance the power of association studies between DLA haplotypes and canine diseases.

Bayesian phylogenetic analysis in BEAST [36] of all unique mainland and island haplotypes (Fig. 3) used the earliest island fox radiocarbon date as a prior estimate for the coalescence of all island fox lineages.

We did however identify two regions where distinct haplotypes have swept in different populations, leading to increased population differentiation.