Sentences with phrase «nucleotide sequence»

Zhang compared the DNA nucleotide sequence of the human version of ASPM to that of two of our great ape cousins, the chimpanzee and the orangutan, as well to more distantly related animals such as rhesus monkeys, seals, dogs, and hamsters.

Rice University scientists have uncovered new details about how a repeating nucleotide sequence in the gene for a mutant protein may trigger Huntington's and other neurological diseases.

This database is produced at National Center for Biotechnology Information (NCBI) as part of the International Nucleotide Sequence Database Collaboration, or INSDC.

However, it may also be possible to use the foldamer approach to develop DNA mimics that can block the action of the many important DNA - binding proteins whose functions depend on the recognition of specific nucleotide sequences.

We describe SSAKE, a tool for aggressively assembling millions of short nucleotide sequences by progressively searching through a prefix tree for the longest possible overlap between any two sequences.

When a protein needs to be created, specific DNA nucleotide sequences are read and copied (transcribed) onto another molecule called RNA.

Telomeres are repetitive nucleotide sequences found at the end of chromosomes which protect them from deteriorating during the process of replication.

Their work arose out of a discovery in the late 1980s of neighboring bacterial DNA segments consisting of repeating nucleotide sequences, which flank short segments.

Stepwise synthesis of a nucleic acid to determine nucleotide sequences; inspired the DNA sequencing technique by F.Sanger (Sanger, Nobel Prize Lecture 2004).

It is a term of art in patent law that renders the claim «open - ended» so that it covers both the listed nucleotide sequence and, more importantly, the listed sequence in combination with additional sequences.

Working with French composer Richard Krüll, the pair turned the complete nucleotide sequences of several microbe genes into compositions based on DNA bases: A (adenosine), C (cytosine), G (guanine), and Thymine (which they have translated to «Re,» or D).

In addition to the RNA / DNA match, the Cas9 enzyme needs to recognize a specific nucleotide sequence called a protospacer adjacent motif (PAM) adjacent to the target DNA.

Identification of physicochemical selective pressure on protein encoding nucleotide sequences Wong, W. S. W., R. Sainudiin, and R. Nielsen.

Detecting selection in noncoding regions of nucleotide sequences Wong, W. S. W. and R. Nielsen.

Silence's specific siRNA molecules exhibit unique structural features which, irrespective of their individual nucleotide sequence, bar third parties from commercialising this type of molecule.

Telomeres are stretches of protective, repetitive nucleotide sequences at the ends of chromosomes.

Microspheres are then able to use proteinoids as templates to make polynucleotides, which are themselves nonrandom because specific three - nucleotide sequences bind preferentially to specific amino acids.

Every tissue in an organism contains a variety of messenger RNA molecules, single - stranded nucleotide sequences bearing instructions for the making of specific proteins.

The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations.

Analysis of partial nucleotide sequences has enabled the team to refine our picture of the evolutionary history of cervids.

Bartlett and Davidson devised a technique called Forensically Informative Nucleotide Sequencing, or FINS, mainly for use in verifying that processed fish products are made of the species they claim to be.

The information content of the genetic code in DNA is not limited to the primary nucleotide sequence of A's, G's, C's and T's.

From a diverse starting population of different DNA or RNA nucleotide sequences, the ones that bind best to the target molecule are selectively enriched, and the process is repeated over multiple «generations.»

A chromosome is, minimally, a very long, continuous piece of DNA, which contains many genes, regulatory elements and other intervening nucleotide sequences.

Animals that share a recent common ancestor would have more nucleotide sequences in common than would more distantly related animals.

The nematode that Lee studies, for example, has more than 15,000 piRNAs with different nucleotide sequences.

In collaboration with Ionis Pharmaceuticals (Carlsbad, CA) they utilized an ASO — an antisense oligonucleotide — a nucleic acid designed by virtue of its complementary nucleotide sequence to bind to the Malat1 lncRNA at a precise location.

They treated the samples with fluorescent probes, molecular tags designed to bind to a particular nucleotide sequence in microbial RNA.

Notophthalmus viridescens, an urodelian amphibian, represents an excellent model organism to study regenerative processes, but mechanistic insights into molecular processes driving regeneration have been hindered by a paucity and poor annotation of coding nucleotide sequences.

These findings present a paradox, however, because latent virus can be of wild - type nucleotide sequence [33], and yet transcription is suppressed.

1981 - The EMBL Data Library is founded — the first central depository of nucleotide sequence data in the world (precursor to EMBL - EBI).

Research interests: The biology of pregnancy, Evolution of genes X environment interactions, Mammalian phylogenetics, Rates of nucleotide sequence evolution, The evolution of the brain, Primate evolutionary genetics

REPAIR has the ability to reverse the impact of any pathogenic G - to - A mutation regardless of its surrounding nucleotide sequence, with the potential to operate in any cell type.

What researchers are trying to do is construct a detailed genetic map of the human genome and determine the entire nucleotide sequence of human deoxyribonucleic acid (DNA).

These measurements can then be used to deduce the underlying nucleotide sequence.

Nucleotide sequence comparisons of the E protein (A), NS5 protein (B) and the genome coding polyprotein (C).

Black versus gray bars indicate observed versus inferred nucleotide sequence.

Searcy, B., Walthers, EA, Heppner, BL, Thompson, RR, Moore, FL. (2009) Identification of mesotocin and vasotocin nucleotide sequences in two species of urodele amphibian.

To ensure that sequence data are freely available, scientific journals require that new nucleotide sequences be deposited in a publicly accessible database as a condition for publication of an article.

(b) Archaeogenomic relatedness results for mtDNA (nucleotide sequence similarity to burial 14) and the nuclear genome.

[The results from the Glasgow experiments provided some evidence that CDRM is principally genetic, and specifically of an «expansion» as noted, in the CAG nucleotide sequence on a gene that yet has to be found or marked.]

Molecular phylogeny of selected decapod crustaceans based on 18S rRNA nucleotide sequences.

There is, however, increasing evidence for changes in gene expression through DNA and chromatin modifications without a change in the inherited nucleotide sequence.

For clarity, nucleotides are drawn on reversion alleles where insertions are present; otherwise, nucleotide sequence corresponds to WT.