Sentences with word «microarray»

Microbial pathogens induce specific host responses or «RNA biosignatures» that can be identified using microarray analyses of blood leukocytes (white cells).

At Berkeley, she developed computationally intensive statistical methods for the analysis of microarray data with applications in cancer biology.

The study results challenge the current paradigm of microarray data analysis and suggest that the new method may improve identification of cancer - associated genes.

In addition, more researchers are realising the benefit of using microarrays in their research programmes.

Scientists at the Royal Institute of Technology (KTH) / SciLifeLab and Fraunhofer EMFT in Germany show how flexible polymer foils are used to integrate electronics, microfluidics and DNA microarray technology for single mutation DNA analysis.

The researchers have developed a large FOV interferometric on - chip lens free microscope (LIM) based on a novel design with a very high axial sensitivity and DOF, applying a technique adequate to be used in microarray platforms for the detection of proteins without the need of labels.

J147 treatment of HT22 cells for one hour increased NGF mRNA by 2.8-fold in a DNA microarray experiment (Table 1) and conditioned medium from J147 treated HT22 cells stimulated neurite growth in PC12 cells in a NGF - dependent manner (Figure 3G).

Research within the Center levarages cross-translational studies that seek to integrate and mine information generated by systems biology platforms such as transcriptome analysis by microarray technology, microRNA profiling, siRNA screens and global proteomic and metabolomic profiling.

There were numerous altered pathways in DS muscle revealed by microarray analysis including the breakdown of proteins, metabolism of glucose and fat, and neuromuscular transmission.

We also describe a method for the bulk testing of the hybridization characteristics of chromosome - specific clones spotted on microarrays by use of DNA amplified from flow - sorted chromosomes.

As a research associate in the pathology labs of Yale School of Medicine, Mrs. Canosa has worked extensively with microarray expression profiling, genotyping, and DNA sequencing.

Validation of tissue microarray technology in breast carcinoma.

CDI utilizes its HuProt ™ Human Proteome Microarray for validating the specificity of the final product.

One of the foremost software products built by Strand for genomics data analysis from microarray experiments was called Soochika.

She's also created artificial bone materials, targets for tuberculosis therapy, cell microarray platforms, and a cell nanoinjector, a device used to inject molecules into living cells.

On combining multiple microarray studies for improved functional classification by whole - dataset feature selection

CDI has produced the ZikaProt ZIKV / DENV protein microarray which contains the proteomes of Asian and African strains of Zika as well as dengue serotypes 1 and 2.

The CDI HuProt microarray contains nearly 75 % of the human proteome on a single glass slide, a unique and powerful tool for high - throughput serum profiling and biomarker discovery.

After initially applying the genomic SNP chromosomal microarray only in fetuses with ultrasound abnormalities, since July 2012, we routinely performed the SNP array also in cases without fetal ultrasound anomalies where invasive prenatal diagnosis was indicated.

Grant 272 (2007) Oligonucleotide Microarray Gene Expression Profiling of Canine Lymphoma Dr. William Kisseberth

As microarray technologies continue to develop, the chemistry underlying the biology will increasingly come to the forefront.

Recently, in investigating preconditioning in the retina, Thiersch et al. [32] reported microarray results for mouse at different time points after 6 h of severe hypoxia (6 % O2).

The current 8 × 60 k Virochip microarrays used in this study contain 19,058 70mer probes representing all viral species in GenBank, and combine probes from all previous Virochip designs [17], [18], [21], [23].

CDI HuProt microarrays are currently being employed in an NIH grant to produce antibodies with absolute specificity to all of the human transcription factors

To understand why only some motor neurons are vulnerable to ALS, the researchers used DNA microarray profiling to compare the activity of tens of thousands of genes in neurons that resist ALS (oculomotor neurons / eye movement and Onuf's nuclei / continence) with neurons affected by ALS (lumbar 5 spinal neurons / leg movement).

«This antibody microarray allowed us to find a number of new cell signalling pathways that were activated or suppressed by an HCV infection,» Professor Doerig said.

Methods: By applying whole - genome oligonucleotide microarray analysis of D. vulgaris and high - efficiency capillary liquid chromatography - tandem mass spectrometry (LC - MS / MS), the group has investigated D. vulgaris grown on various electron donors or under stress conditions.

B. Heatmap depicts normalized intensities of microarray probes contained in promoters (at most one per promoter) that best differentiate between CPA and control groups.

Therefore, before publication, large data sets (including microarray data, protein or DNA sequences, atomic coordinates or electron microscopy maps for molecular and macromolecular structures, and climate data) must be deposited in an approved database and an accession number or a specific access address must be included in the published paper.

The University Health Network's Microarray Centre was established as part of a consortium of research institutions in Toronto.

Breeden, Prentice and Zhao, whose study appeared in the May 8 Proceedings of the National Academy of Sciences, compared their new algorithm to other methods used to analyze microarray experiments designed to identify cell cycle genes in yeast.

DNA microarray chips are used to detect missing segments of chromosomes (deletions) or additional segments (duplications) that may be too small to be seen by karyotype.

Remember that GWAS studies use «SNP chips» — high density microarrays which genotype 500,00 to 1 million SNPs simultaneously — whose markers are generally chosen for their informativeness, not necessarily their potential causation.

Our mission is to ensure that Canadian scientists have access to high - quality microarrays at an affordable price, as well as access to technical and professional support.

The Sequencing and Microarray Facility provides essential genomic analysis services to support researchers in basic science, translational, and populationbased research programs

The strengths of this study include our unique tissue microarray design, containing matched primary and metastatic tissue from the same patient.

Slides were scanned at 3 µm resolution using an Agilent DNA Microarray Scanner.

Individual 45 - mer oligonucleotides corresponding to mRNAs of each gene were used as probes, and immobilized on microarray slides, as described below.

In this study, we employed a pan-viral microarray assay, the Virochip, to identify a novel adenovirus associated with a fulminant pneumonia outbreak in a colony of New World titi monkeys.

(A — B) The log10 FPKM expression values obtained from RNAseq are plotted against the normalized expression estimates from an Illumina microarray chip for the VNO (A) and OM (B), 1 was added to avoid computing log10 (0).

Xu applied the DNA microarray technique to screen more than 100,000 genes in the human genome to find the exact gene regulation pathway.

Detection of elafin as a candidate biomarker for ulcerative colitis by whole - genome microarray screening

Natera uses a SNP microarray from Ilumina with a proprietary technology called Parental Support ™, which tests all 24 chromosomes and delivers results that are typically > 99 % accurate.

Subjecting N. gonorrhoeae to the phenotypic microarray screening method for the first time, Sikora's team focused on seven proteins from the bacteria's cell envelope, which consists of the outer membrane, the cell wall and the inner membrane.

The result is a cell microarray of 10,000 distinct spots, each acting like a little protein factory.