Sentences with phrase «gene variants»

This is the prospect raised by the discovery of gene variants that seem to predict whether an individual will produce enough antibodies in response to a vaccine to protect them against disease.

In this study we found that individuals with gene variants that lead to increased body - mass index (BMI) also had an increased risk of heart failure and diabetes.

They applied the same analytic techniques to tease out connections between all 1,600 known transcription factors and the known gene variants associated with more than 200 diseases.

Examples include modern human gene variants for cognitive development.

The test scanned for about one million of the roughly 10 million gene variants in the human genome.

In most cases, the researchers know only of the association with the identified gene variants, and not what the genes might specifically do.

Their goal is a database that will help them examine how specific gene variants affect health.

What the other four gene variants do is less clear, but they could be an evolutionary response to selective pressures besides high altitude.

But what about people who have inherited gene variants known to increase risk?

Now, researchers have discovered a handful of new gene variants responsible for this palette of tones.

Patients who test positive may carry certain gene variants that increase the risk of passing along a genetic condition to future offspring — key insight for both patients and clinicians.

When exposed to estrogen, an area in the brain's memory hub that is typically suppressed during such tasks instead activated in those with the uniquely human gene variant.

Comparing the two sets of genes, the team discovered several immune - related gene variants that were rare among the living.

Without knowing which gene variants were contributing useful properties, people simply selected the best plants for continued cultivation, in this case choosing plants that had large backpacks.

The researchers said their finding could lead to new treatments that might help ease symptoms of menopause, but more research is needed to understand how other rare gene variants could affect hot flashes.

A special gene variant increases the risk of heavy smoking.

While those studies identified several gene variants that appeared to increase the risk of each disorder, none of the associations were strong enough to meet the strict standards of genome - wide significance.

Then he sent the new gene variants into the cell, where the bacteria's own machinery for self - assembling DNA took over and incorporated the genes into the genome.

However, the research team now reports that menopause may begin at an earlier age in white female smokers who are carriers of two different gene variants.

Three of the darker - skin gene variants appear to have evolved from variants linked with less pigment.

The new study should help by identifying distinct populations in which to look for medically important gene variants.

The investigated gene variants are present in around 1/3 of the population, so they are common variants with small effect size.

Strong swimming sperm's secret A gene variant can make sperm strong and speedy, a study of wild mice suggests.

The big - ticket item in the budget — $ 1 million a year — is to scan Finnish DNA for promising gene variants.

We use genetic approaches to identify novel genes and gene variants affecting the development in humans.

Scientists are now thinking that DNA might play a role in the way the body processes caffeine, with a certain gene variant slowing the metabolism of coffee.

However, if a pregnant mother does not have good nutrition, her baby's immune system is less likely to activate the cancer - fighting gene variant.

From the sequence data, they found gene variants indicating that the man had dark skin and eyes.

Researchers have assumed that mothers are more likely to pass on autism - promoting gene variants.

The beneficial gene variant — for a type of serotonin receptor — is far more common in whites than in blacks.

So gene variants that have been selected for are often found surrounded by the same stretches of DNA, whereas those that have not been selected do not have consistent genetic neighbours.

More recently, improved gene - sequencing technology and larger population studies have made it possible to detect gene variants that appear in only 1 percent of the human population.

Next - generation DNA - sequencing developments will push the cost of DNA sequencing down to the point that anyone can afford to have complete knowledge of their personal gene variants.

Interestingly, the team also found the spread of two gene variants associated with celiac disease.

There are a number of gene variants that may hold the key to a healthy old age life.

For eight of these sites, the researchers were able to identify a specific gene variant that influences risk for both diseases.

Having more schizophrenia risk - related gene variants was also associated with a greater decline in lifelong cognitive ability.

A statistical algorithm then analyzes which gene variants the fetus has inherited from each parent and detects new mutations in the child's DNA.

New gene variants have arisen and spread among humans in the recent past.

The selection process increases the likelihood that certain gene variants will be passed on, along with the risk for undesirable health issues.

ASHG 2015: Common Gene Variant Linked to Chromosome Errors and Early Pregnancy Loss ASHG Press Release — October 8, 2015

«While this study does not show that these common gene variants produce schizophrenia per se, it elegantly suggests that these variants may contribute to declines in intelligence, a clinical feature associated with schizophrenia,» commented Dr. John Krystal, Editor of Biological Psychiatry.

According to senior researcher Shoukhrat Mitalipov, «Every generation on would carry this repair because we've removed the disease - causing gene variant from that family's lineage.»

Subjects were individuals who had a history of heart attack and / or coronary artery disease and who carry one or more of the at - risk gene variants deCODE has linked to heart attack.

Slow - healing or non-healing bone fractures in otherwise healthy people may be caused by gene variants that are common in the population, according to Penn State College of Medicine researchers.

Mekile says she plans to use her award to establish a link between gene variants in patients and autism - like neurological disorders.

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution.

In principle, identifying specific gene variants as risk factors for poor fracture healing would lead not only to the development of patient screening tests, but also to a better understanding of the basic biology of how fractures heal.

To illustrate how it works in practice, Koenig offers the example of a professional hockey player whose profile shows that he has gene variants found in people who respond rapidly to lactic - acid threshold training.