Sentences with phrase «cell surface»

Various receptors which can either activate or inhibit the cell have been identified on cell surface.

This communication involves the release of chemicals from neurons that stimulate cell surface receptors on other neurons.

The data referred to cell surface proteins that supposedly defined the cells.

The process binds an originally inactive form of drug chemotherapy, with an enzyme, to prostate cancer - specific proteins on tumor cell surfaces and detects the drug's absorption into the tumor.

They found that the protein allows the malaria parasite to recognize and attach to the red blood cell surface.

Scientists suspected that cell surfaces contained some kind of recipient for hormones, but didn't know what they looked like or how they worked.

First, we wanted to determine whether the observed regional gradation of expression of cell surface markers of pluripotency was reflected in patterns of pluripotency gene expression, and second, we wanted to compare these results, obtained from cells subjected to minimal manipulation, to those from cells that were separated by flow cytometry in subsequent experiments.

Lipke, who specializes in the structure and function of cell surface markers in yeasts, says Rezende was as independent as a typical late - term Ph.D. student.

Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression.

New cells surface in a matter of days, instead of weeks, piling up faster than they're shed.

The team used patterned photoactivation non-linear SIM to produce videos showing structural proteins break down and reassemble themselves as cells move and change shape, as well as the dynamics of tiny pits on cell surfaces called caveolae.

A Postdoctoral Research Associate Position is available funded by the Wellcome Trust, to study the nanoscale organisation of human immune cell surfaces by super-resolution fluorescence microscopy.

With similar precision, Professor Bargmann has also identified many of the intracellular signalling pathways in C. elegans that relay information from cell surface odorant receptors (G protein - coupled receptors) to the interior of each sensory neuron.

Amongst the populations that expressed HIGH or MID levels of stem cell surface antigens, coexpression of transcripts for endoderm or mesoderm genes predominated, but in the LOW and NEG populations, there were significant numbers of cells expressing neural lineage markers, in particular Pax - 6 (Figure 3d).

They identified these cells by looking for cell surface proteins called CD31 and CD146.

Most cells that are positive for stem cell surface markers express Oct - 4, but only those towards the top of the hierarchy express the nodal receptor TDGF - 1 and the growth factor GDF3.

In the case of additional labelling of specific cell surface proteins, primary antibodies were added at a dilution of 1 ∶ 1000 to cells resuspended in FACs buffer.

Characterization and functionality of cell surface molecules on human mesenchymal stem cells.

The external face of the flavivirus NS1 protein (sugars in grey balls) is exposed on infected cell surfaces where it can interact with the immune system.

D'Oro, U., Vacchio, M.S., Weissman, A.M. & Ashwell, J.D. Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation.

Cells were stained with antibodies specific for human cell surface markers: CD326 / ESA - FITC, CD24 - PE, and CD44 - PE - Cy7 (BD Pharmingen, San Jose, CA, USA).

One factor that facilitated their device's progress was the use of room temperature ionic liquid (RTIL), a gel that serves to stabilize the microenvironment at the skin - cell surface so that a week's worth of hourly readings can be taken without the performance degrading over time.

In the neuromuscular juncture, Mei's lab found several years back that LRP4 on the muscle cell surface is a receptor for agrin, a protein that motor neurons release to direct construction of the nerve - muscle juncture.

CARs teach T cells to recognize specific cancer cell surface markers, or antigens, and then go on the attack against cells with those markers.

Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified the presence of this protein, called CD55, found to be critical to the Plasmodium falciparum parasite's ability to attach itself to the red blood cell surface during invasion.

In addition, exhausted CD8 T cells start to express inhibitory cell surface receptors that receive and feed inhibitory signals into the cell establishing a negative feedback loop.

Current studies focus mainly on two receptor systems - the mast cell surface receptor, FcεRI, and the receptor for epidermal growth factor that operate in immunological and cell proliferation responses.

The putative merozoite cell surface and secreted proteins that were chosen for recombinant expression

To improve the safety of CAR - T treatment, researchers are now engineering «suicide switches» into the cells, genetically encoded cell surface receptors that trigger the cell to die when a small molecule drug binds them.

These immune cell surface proteins in themselves help the body by making our DNA less vulnerable to attack by our immune system which may have gone on the attack of foreign particles in our blood, such as dead cells, parasites, viruses, pollens and more.

Next, we characterized CXCR4 cell surface expression over time by FACS.

For kinetic analysis, injections over reference cell surface and injections with buffer were subtracted from the data.

The immune system recognizes transplanted organs as foreign tissue by telltale proteins, called the major histocompatibility complex (MHC), that coat cell surfaces.

There, I set up a «biomechanics» lab to study the physical properties of bacterial cell surface polymers and their relevance to cell shape and continued to read about cell division and other subjects.

As SNX27 plays an important role in shuttling the AMPA - receptor to the brain cell surface, lower levels of SNX27 means fewer receptors are carried to the surface, which consequently interrupts the signal transmission and impairs memory.

The flawed data did not contradict the paper's main claim that the injected cells have a potential similar to that of embryonic stem cells, researchers say, because they could simply have had other cell surface proteins not included in the data.

Every T cell type expresses different cell surface markers and secretes different cytokines.

Upon further analysis of these fetal muscle cells two new cell surface markers called ERBB3 and NGFR were discovered; this enabled the reserchers to precisely isolate muscle cells from human tissue and separate them from various cell types created using human pluripotent stem cells.

«Effectively, the virus» haemagglutinin - neuraminidase reacts with a carbohydrate to form an intermediate that then is hydrolysed, enabling the virus to escape from the infected cell surface and cause further infection.

In a first step, the water - soluble toxin assembles at the target cell surface around this core design, which makes the cell unable to repair the damage resulting from aerolysin pore formation.

Endocytosis has traditionally been viewed as a mechanism for achieving signal attenuation: activated cell surface receptors are internalised and trafficked through endocytic vesicles to lysosomes, where they are degraded.

Current treatments focus on modulating cell surface receptor response, especially dopamine receptors.

Moreover, the intact mAb 5.91 was able to bind the free IgE to prevent it from binding cell surface receptors.

Internalization of POS is observed in a single optical y - axis projection (< 1 µm) of pigmented iPS - RPE cells labelled with the apical cell surface marker ATP1B1 (red).